| 30th Aug 2017 7:00 am | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 9th Aug 2017 7:00 am | 
                                            RNS | 
                                            REVIVE 2 Trial Last Patient Treated | 
                                        
                                                                            
                                            | 18th Jul 2017 7:00 am | 
                                            RNS | 
                                            Amendment to Amphion Consultancy Agreement | 
                                        
                                                                            
                                            | 6th Jul 2017 7:00 am | 
                                            RNS | 
                                            PRESENTING THREE POSTERS ON ICLAPRIM AT ID WEEK | 
                                        
                                                                            
                                            | 28th Jun 2017 12:41 pm | 
                                            RNS | 
                                            Exercise of warrants | 
                                        
                                                                            
                                            | 27th Jun 2017 7:00 am | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 22nd Jun 2017 3:20 pm | 
                                            RNS | 
                                            Result of General Meeting | 
                                        
                                                                            
                                            | 22nd Jun 2017 7:00 am | 
                                            RNS | 
                                            Presents at ID Week 2017 | 
                                        
                                                                            
                                            | 15th Jun 2017 5:42 pm | 
                                            RNS | 
                                            Results of Annual General Meeting | 
                                        
                                                                            
                                            | 14th Jun 2017 7:00 am | 
                                            RNS | 
                                            Presentation at BIO International Convention | 
                                        
                                                                            
                                            | 8th Jun 2017 2:32 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 5th Jun 2017 6:20 pm | 
                                            RNS | 
                                            Publication of Shareholder Circular | 
                                        
                                                                            
                                            | 2nd Jun 2017 4:36 pm | 
                                            RNS | 
                                            Result of Placing | 
                                        
                                                                            
                                            | 2nd Jun 2017 7:00 am | 
                                            RNS | 
                                            Proposed Placing | 
                                        
                                                                            
                                            | 23rd May 2017 4:40 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 23rd May 2017 4:35 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 18th May 2017 7:00 am | 
                                            RNS | 
                                            Publication of UK Annual Report and Accounts | 
                                        
                                                                            
                                            | 10th May 2017 7:00 am | 
                                            RNS | 
                                            Appointments to Scientific Advisory Board | 
                                        
                                                                            
                                            | 5th May 2017 7:00 am | 
                                            RNS | 
                                            Directorate Change | 
                                        
                                                                            
                                            | 2nd May 2017 3:10 pm | 
                                            RNS | 
                                            Exercise of Warrants and Issue of Equity | 
                                        
                                                                            
                                            | 2nd May 2017 7:00 am | 
                                            RNS | 
                                            Annual Financial Report | 
                                        
                                                                            
                                            | 28th Apr 2017 12:00 pm | 
                                            RNS | 
                                            Change of Adviser | 
                                        
                                                                            
                                            | 24th Apr 2017 7:00 am | 
                                            RNS | 
                                            Notification of change in holding of shareholder | 
                                        
                                                                            
                                            | 18th Apr 2017 7:00 am | 
                                            RNS | 
                                            Positive Data Readout for Iclaprim Phase 3 Trial | 
                                        
                                                                            
                                            | 12th Apr 2017 3:06 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 12th Apr 2017 3:01 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 31st Mar 2017 4:15 pm | 
                                            RNS | 
                                            Change of Registered Office | 
                                        
                                                                            
                                            | 8th Feb 2017 2:57 pm | 
                                            RNS | 
                                            Investor Presentation | 
                                        
                                                                            
                                            | 8th Feb 2017 7:00 am | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 7th Feb 2017 7:02 am | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 31st Jan 2017 3:36 pm | 
                                            RNS | 
                                            Hardman Research: Further de-risking of iclaprim | 
                                        
                                                                            
                                            | 31st Jan 2017 7:00 am | 
                                            RNS | 
                                            Clinical trial finishes patient treatment phase | 
                                        
                                                                            
                                            | 27th Jan 2017 6:13 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 18th Jan 2017 7:05 am | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 18th Jan 2017 7:00 am | 
                                            RNS | 
                                            Appointment of Chief Financial Officer | 
                                        
                                                                            
                                            | 9th Jan 2017 5:28 pm | 
                                            RNS | 
                                            Issue of Equity | 
                                        
                                                                            
                                            | 3rd Jan 2017 12:31 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 30th Dec 2016 3:09 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 30th Dec 2016 2:38 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 21st Dec 2016 5:50 pm | 
                                            RNS | 
                                            Conversion of CPNs, PDMR Dealing & TVR |