| 24th Jun 2019 7:00 am | 
                                            RNS | 
                                            Motif Bio Presents New Iclaprim Data - ASM Microbe | 
                                        
                                                                            
                                            | 20th Jun 2019 4:35 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 19th Jun 2019 5:08 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 18th Jun 2019 4:05 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 14th Jun 2019 9:04 am | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 12th Jun 2019 5:52 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 6th Jun 2019 7:00 am | 
                                            RNS | 
                                            Receipt of FDA Meeting Minutes | 
                                        
                                                                            
                                            | 31st May 2019 3:15 pm | 
                                            RNS | 
                                            Result of AGM | 
                                        
                                                                            
                                            | 31st May 2019 10:28 am | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 29th May 2019 11:36 am | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 22nd May 2019 1:50 pm | 
                                            RNS | 
                                            AGM Statement | 
                                        
                                                                            
                                            | 22nd May 2019 7:00 am | 
                                            RNS | 
                                            Orphan Disease Opportunity for Iclaprim | 
                                        
                                                                            
                                            | 21st May 2019 7:00 am | 
                                            RNS | 
                                            Iclaprim Data presented at ASM Microbe 2019 | 
                                        
                                                                            
                                            | 20th May 2019 6:14 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 3rd May 2019 6:25 pm | 
                                            RNS | 
                                            Meeting with US FDA held as planned | 
                                        
                                                                            
                                            | 1st May 2019 7:00 am | 
                                            RNS | 
                                            Motif Signs Agreement with Lamellar Biomedical | 
                                        
                                                                            
                                            | 26th Apr 2019 7:01 am | 
                                            RNS | 
                                            Notice of AGM | 
                                        
                                                                            
                                            | 26th Apr 2019 7:00 am | 
                                            RNS | 
                                            Appointment of Andrew Powell to Board of Directors | 
                                        
                                                                            
                                            | 16th Apr 2019 7:00 am | 
                                            RNS | 
                                            Motif Presents New Iclaprim Data at ECCMID 2019 | 
                                        
                                                                            
                                            | 15th Apr 2019 7:00 am | 
                                            RNS | 
                                            Fiscal Year 2018 Results | 
                                        
                                                                            
                                            | 4th Apr 2019 7:00 am | 
                                            RNS | 
                                            Motif Bio to Present Iclaprim Data at ECCMID 2019 | 
                                        
                                                                            
                                            | 2nd Apr 2019 5:43 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 1st Apr 2019 3:28 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 1st Apr 2019 2:17 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 26th Mar 2019 7:00 am | 
                                            RNS | 
                                            Motif Bio Raises £2.7m (US$3.55m) | 
                                        
                                                                            
                                            | 25th Mar 2019 9:49 am | 
                                            RNS | 
                                            Proposed Equity Fundraise | 
                                        
                                                                            
                                            | 20th Mar 2019 7:00 am | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 20th Mar 2019 7:00 am | 
                                            RNS | 
                                            Motif Bio Granted Meeting with U.S. FDA | 
                                        
                                                                            
                                            | 18th Mar 2019 7:00 am | 
                                            RNS | 
                                            Appointment of Bruce Williams as Interim Chairman | 
                                        
                                                                            
                                            | 15th Mar 2019 7:01 am | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 7th Mar 2019 12:07 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 7th Mar 2019 12:02 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 19th Feb 2019 7:00 am | 
                                            RNS | 
                                            Conference Call and Webcast | 
                                        
                                                                            
                                            | 18th Feb 2019 7:00 am | 
                                            RNS | 
                                            Amendment Agreement with Hercules Capital | 
                                        
                                                                            
                                            | 15th Feb 2019 4:28 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 15th Feb 2019 4:26 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 14th Feb 2019 7:00 am | 
                                            RNS | 
                                            Complete Response Letter from the FDA | 
                                        
                                                                            
                                            | 5th Feb 2019 7:00 am | 
                                            RNS | 
                                            Exercise of Warrants | 
                                        
                                                                            
                                            | 23rd Jan 2019 4:31 pm | 
                                            RNS | 
                                            Exercise of Warrants | 
                                        
                                                                            
                                            | 1st Nov 2018 4:40 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn |