| 26th Nov 2019 7:00 am | 
                                            RNS | 
                                            Voluntary Delisting from the Nasdaq Capital Market | 
                                        
                                                                            
                                            | 20th Nov 2019 5:51 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 18th Nov 2019 12:12 pm | 
                                            RNS | 
                                            Directorate Changes | 
                                        
                                                                            
                                            | 14th Nov 2019 6:13 pm | 
                                            RNS | 
                                            Result of General Meeting | 
                                        
                                                                            
                                            | 11th Nov 2019 7:00 am | 
                                            RNS | 
                                            Settlement Agreement | 
                                        
                                                                            
                                            | 28th Oct 2019 4:14 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 25th Oct 2019 3:51 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 25th Oct 2019 12:07 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 25th Oct 2019 12:02 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 25th Oct 2019 7:00 am | 
                                            RNS | 
                                            Posting of Circular and Notice of General Meeting | 
                                        
                                                                            
                                            | 24th Oct 2019 7:00 am | 
                                            RNS | 
                                            U.S. Army-funded project to Evaluate Iclaprim | 
                                        
                                                                            
                                            | 21st Oct 2019 3:00 pm | 
                                            RNS | 
                                            Timing of General Meeting and Circular | 
                                        
                                                                            
                                            | 21st Oct 2019 12:07 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 21st Oct 2019 12:02 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 10th Oct 2019 7:00 am | 
                                            RNS | 
                                            Motif Bio confirms receipt of FDA meeting minutes | 
                                        
                                                                            
                                            | 3rd Oct 2019 12:07 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 3rd Oct 2019 12:02 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 3rd Oct 2019 7:00 am | 
                                            RNS | 
                                            Change of Adviser | 
                                        
                                                                            
                                            | 2nd Oct 2019 7:00 am | 
                                            RNS | 
                                            Conditional Placing | 
                                        
                                                                            
                                            | 30th Sep 2019 4:40 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 30th Sep 2019 4:35 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 30th Sep 2019 2:22 pm | 
                                            RNS | 
                                            Half-year Report | 
                                        
                                                                            
                                            | 17th Sep 2019 4:41 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 17th Sep 2019 4:35 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 4th Sep 2019 2:57 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 2nd Sep 2019 7:00 am | 
                                            RNS | 
                                            Amended Loan and Security Agreement | 
                                        
                                                                            
                                            | 30th Aug 2019 4:41 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 30th Aug 2019 4:35 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 19th Aug 2019 7:00 am | 
                                            RNS | 
                                            NIH to Evaluate Iclaprim Activity against Listeria | 
                                        
                                                                            
                                            | 1st Aug 2019 7:00 am | 
                                            RNS | 
                                            Amended Loan and Security Agreement | 
                                        
                                                                            
                                            | 26th Jul 2019 7:00 am | 
                                            RNS | 
                                            Receipt of Deficiency Notice from Nasdaq | 
                                        
                                                                            
                                            | 26th Jul 2019 7:00 am | 
                                            RNS | 
                                            Motif Bio Confirms Meeting Date with U.S. FDA | 
                                        
                                                                            
                                            | 19th Jul 2019 7:00 am | 
                                            RNS | 
                                            Motif Bio-Receipt of Deficiency Notice from Nasdaq | 
                                        
                                                                            
                                            | 18th Jul 2019 4:30 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 15th Jul 2019 7:00 am | 
                                            RNS | 
                                            US FDA meeting request and package submitted | 
                                        
                                                                            
                                            | 28th Jun 2019 5:13 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 28th Jun 2019 4:40 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 28th Jun 2019 4:36 pm | 
                                            RNS | 
                                            Price Monitoring Extension | 
                                        
                                                                            
                                            | 26th Jun 2019 12:07 pm | 
                                            RNS | 
                                            Second Price Monitoring Extn | 
                                        
                                                                            
                                            | 26th Jun 2019 12:02 pm | 
                                            RNS | 
                                            Price Monitoring Extension |