(Alliance News) - Stock prices in London were higher at midday on Thursday, as gains for telecom stocks helped the FTSE 100 edge into positive territory, while investors digested stronger UK services activity and rising inflationary pressures in Europe. Read More
(Alliance News) - The following are the leading risers and fallers among London Main Market small-cap and AIM stocks on Thursday. Read More
(Alliance News) - Hutchmed China PLC on Thursday announced that its subsidiary, Hutchmed Ltd, has entered into an exclusive development licence agreement with a subsidiary of GSK PLC. Read More
(Alliance News) - M&G swings to a first-half pretax loss attributable to equity holders as short-term investment fluctuations weigh on statutory results, while LondonMetric Property announces GBP105 million of investment activity. Elsewhere, Jet2 says trading remains strong and announces plans to move from AIM to London's Main Market. Read More
Hutchmed China Ltd - Hong Kong-based biopharmaceutical company - Announces "positive high-level results" from the Sanovo China phase 3 trial of Orpathys plus Tagrisso in treatment-naive patients with locally advanced or metastatic non-small cell lung cancer, whose tumours harbour epidermal growth factor receptor mutation and MET overexpression. Orpathys, or savolitinib, combined with Tagrisso or osimertinib, showed "a statistically significant and highly clinically meaningful improvement in progression-free survival" in the high MET and intention-to-treat patient populations, compared with Tagrisso alone. Hutchmed adds that "the combination also demonstrated a very encouraging clinical benefit in [the secondary endpoint of] overall survival" in both populations. Hutchmed is jointly developing Orpathys with AstraZeneca, which is also commercialising the treatment. Read More
(Alliance News) - UK house price growth remains subdued in August despite a modest monthly recovery. Bunzl upgrades its full-year outlook and announces a GBP500 million share buyback, while Bodycote and Gamma Communications accept takeover offers. Read More
(Alliance News) - Hutchmed China Ltd on Friday announced regulatory approval for fanregratinib in China for the treatment of intrahepatic cholangiocarcinoma, a rare cancer that develops in the bile ducts. Read More
(Alliance News) - Goodwin hails record annual profit as a process to sell a unit progresses, Morgan Advanced Materials has exited an investee, netting over GBP50 million, while McBride has secured a deal with a former Reckitt unit. Read More
(Alliance News) - AstraZeneca PLC on Monday announced it is discontinuing the eVOLVE-Lung02 phase III trial after an independent review found its experimental drug volrustomig was unlikely to improve outcomes against the comparator treatment. Read More
(Alliance News) - Hutchmed China Ltd on Thursday announced regulatory approval for savolitinib, brand name 'ORPATHYS', for a form of gastric cancer with "a very poor prognosis". Read More
(Alliance News) - Stock prices in London were mixed at midday on Thursday, as the FTSE 100 outperformed the mid-cap index as investors focused on the upcoming US jobs report for further clues on the Federal Reserve's interest rate path. Read More
(Alliance News) - The following are the leading risers and fallers among London Main Market small-cap and AIM stocks on Thursday. Read More
(Alliance News) - Hutchmed China Ltd on Thursday reported positive phase two data for fanregratinib in patients with intrahepatic cholangiocarcinoma, showing clinically meaningful and durable responses in a registration-enabling study. Read More
(Alliance News) - Hutchmed China Ltd on Friday said phase III trial results for its investigational drug sovleplenib showed significant efficacy and a favourable safety profile in patients with warm antibody autoimmune hemolytic anaemia, or wAIHA. Read More
(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Thursday and not separately reported by Alliance News: Read More
(Alliance News) - The following is a round-up of earnings and trading updates by London-listed companies, issued on Wednesday and not separately reported by Alliance News: Read More
(Alliance News) - Hutchmed China Ltd on Monday said it had begun phase-three clinical trials of its lymphoma treatment in China. Read More
(Alliance News) - GSK makes regulatory progress in Japan for a cancer therapy, Anglo American moves to delist from the Swiss exchange as part of its restructuring, and Applied Nutrition reports strong interim growth while holding back on shareholder payouts. Read More