| 11th Jun 2013 5:24 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 10th Jun 2013 5:11 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 7th Jun 2013 5:20 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 6th Jun 2013 5:39 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 5th Jun 2013 5:16 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 5th Jun 2013 5:06 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 5th Jun 2013 2:03 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 4th Jun 2013 5:32 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 3rd Jun 2013 5:46 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 3rd Jun 2013 2:14 pm | 
                                            RNS | 
                                            Total Voting Rights | 
                                        
                                                                            
                                            | 31st May 2013 5:46 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 30th May 2013 5:25 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 29th May 2013 5:07 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 28th May 2013 5:21 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 28th May 2013 4:05 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 24th May 2013 5:11 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 23rd May 2013 5:18 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 21st May 2013 5:16 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 20th May 2013 5:14 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 17th May 2013 5:58 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 17th May 2013 4:12 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 17th May 2013 2:34 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 17th May 2013 9:51 am | 
                                            RNS | 
                                            Blocklisting Interim Review | 
                                        
                                                                            
                                            | 16th May 2013 4:23 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 15th May 2013 6:07 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 15th May 2013 5:38 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 14th May 2013 6:27 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 14th May 2013 5:29 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 13th May 2013 5:53 pm | 
                                            RNS | 
                                            Transaction in Own Shares | 
                                        
                                                                            
                                            | 13th May 2013 5:01 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 13th May 2013 5:01 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 13th May 2013 4:55 pm | 
                                            RNS | 
                                            Doc re. (AGM Statement) | 
                                        
                                                                            
                                            | 13th May 2013 4:54 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 10th May 2013 5:31 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 10th May 2013 5:03 pm | 
                                            RNS | 
                                            Breo Ellipta FDA Approval | 
                                        
                                                                            
                                            | 8th May 2013 4:12 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 8th May 2013 12:23 pm | 
                                            RNS | 
                                            Additional Listing | 
                                        
                                                                            
                                            | 7th May 2013 5:21 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 2nd May 2013 5:56 pm | 
                                            RNS | 
                                            Corporate Responsibility Committee member change | 
                                        
                                                                            
                                            | 1st May 2013 5:32 pm | 
                                            RNS | 
                                            Result of AGM |