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Notification of Interest

12th Apr 2007 11:00

Bionostics PLC12 April 2007 11 April 2007 TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Identity of the issuer or the underlying issuer of existing shares to whichvoting rights are attached (ii):Bionostics PLC 2. Reason for the notification (please state Yes/No): ( ) An acquisition or disposal of voting rights: ( ) An acquisition or disposal of financial instruments which may result in theacquisition of shares already issued to which voting rights are attached: ( ) An event changing the breakdown of voting rights: ( ) Other (please specify) : Yes. Restatement of historic interest in compliancewith the FSA's new disclosure and transparency rules 3. Full name of person(s) subject to the notification obligation (iii):Barclays PLC 4. Full name of shareholder(s) (if different from 3.) (iv):Barclays Bank PLCBarclays Global Investors LtdBarclays Life Assurance Co LtdBarclays Stockbrokers LtdGerrard Ltd 5. Date of the transaction (and date on which the threshold is crossed orreached if different) (v):16 March 2007 6. Date on which issuer notified:19 March 2007 7. Threshold(s) that is/are crossed or reached:10% 8. Notified details:................. A: Voting rights attached to shares Class/type of Situation previous Resulting situation after the triggering shares to the Triggering transaction (vii)if possible transcation (vi)use ISIN CODE Number Number Number of Number of voting % of voting rights of of Voting shares rights (ix) Shares Rights Direct Direct Indirect Direct Indirect (viii) (x) (xi) GB0008381823 n/a n/a 5,065,303 0 5,065,303 0.00 10.05 B: Financial InstrumentsResulting situation after the triggering transaction (xii) Type of Expiration date Exercise/Conversion Number of voting % of votingfinancial (xiii) Period/Date (xiv) rights that may be rightsinstrument acquired if the instument is exercised/converted N/A Total (A+B) Number of voting rights % of voting rights5,065,303 10.05 9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable (xv):Barclays Bank PLCBarclays Global Investors LtdBarclays Life Assurance Co LtdBarclays Stockbrokers LtdGerrard Ltd Proxy Voting: 10. Name of the proxy holder:................. 11. Number of voting rights proxy holder will cease to hold:................. 12. Date on which proxy holder will cease to hold voting rights:................. 13. Additional information:................. 14. Contact name:Simon Dighton, Bionostics PLC 15. Contact telephone number:01993 885070 This information is provided by RNS The company news service from the London Stock Exchange

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