Notice of intention to appoint Administrators

The information communicated within this announcement is deemed to constitute inside information as stipulated under the Market Abuse Regulations (EU) No. 596/2014 as it forms part of UK domestic law by virtue of the European Union (Withdrawal) Act 2018 ("MAR"), and is disclosed in accordance with the Company's obligations under Article 17 of MAR. Upon the publication of this announcement, this inside information is now considered to be in the public domain.

Trellus Health plc

("Trellus Health" or the "Company") 

Notice of intention to appoint Administrators

Trellus Health plc (AIM: TRLS), a healthcare company delivering Trellus Elevate®, a digital platform that integrates data analytics with personalised, scientifically proven resilience programmes and value-based solutions to manage complex chronic conditions, announces that further to the notification of 12 August 2026, the Board of Trellus Health has concluded that the Company has insufficient funds to continue trading as a going concern. The Board has therefore filed a notice of intention to appoint Paul Zalkin and Tom Parish of Quantuma Advisory Ltd as administrators of the Company.

The Board has resolved to take this action to protect the interests of creditors. Unless circumstances change, and in accordance with statutory requirements, the Board intends to appoint administrators within 5 business days.

The Board is also continuing, in conjunction with its corporate restructuring advisers, with its previously notified efforts to seek a buyer for certain of the Company's assets including the shares in Trellus Health Inc., the Company's US operating subsidiary. The Board expects, should any sale be successfully concluded, that there will be no returns to the Company's shareholders.

The Company's ordinary shares remain suspended from trading on AIM effective 8 May 2026. Further announcements will be made as appropriate.

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About Trellus Health plc (www.trellushealth.com)

Trellus Health® (AIM: TRLS) is a healthcare company providing value-based innovative solutions and services, helping people with chronic conditions take control of their health through a proven, scientifically validated self-management solution and continuous, personalised support. Trellus Health's approach empowers patients to better navigate the emotional and physical challenges of their conditions, leading to significant cost savings, enhanced treatment adherence, and long-term, sustainable health outcomes.

Trellus Health® integrates its proprietary resilience-based methodology with the technology, tools, and expert coaching and educator team to deliver Trellus Elevate®, a whole-person technology-enhanced condition management platform. The Company is initially focusing on chronic costly GI conditions that have a high mental health burden, such as Inflammatory Bowel Disease (IBD). Among IBD patients, applying the Trellus Elevate® methodology resulted in over 90% fewer hospitalisations and a reduction of over 70% in emergency room visits. Given the common emotional and mental health struggles associated with a variety of chronic conditions and therapeutic areas, Trellus Health® considers its approach to have potential utility and demand across many conditions.

The Company also offers Trellus TrialSet™, a solution for pharmaceutical partners spanning clinical trials to commercialisation, applying the same validated resilience science and platform to support trial success and long-term patient engagement

The Company was founded by Icahn School of Medicine at Mount Sinai faculty members Marla C. Dubinsky, MD, and Laurie Keefer, PhD, both world-leading experts in treating both the physical and emotional impacts of IBD, with a combined 50 years of pioneering whole-person healthcare innovation.

Shares in Trellus Health were admitted to trading on AIM in May 2021, under the ticker TRLS. For more information, visit: www.trellushealth.com