12th Nov 2024 19:50
Merck & Co Inc and AstraZeneca PLC - Pharmaceutical companies based in Rahway, New Jersey and Cambridge, England, respectively - Phase 3 Komet trial shows statistically significant and clinically meaningful improvement in objective response rate in adult neurofibromatosis patients treated with AstraZeneca and Merck's joint-developed medication Koselugo. The condition is a rare progressive genetic disease in which tumours develop on nerve sheaths and may lead to disfigurement, motor dysfunction, pain, airway dysfunction, visual impairment and bladder or bowel dysfunction. Koselugo is approved to treat children with the disease but there is little intervention available for adults. Read More