| 4th May 2020 1:58 pm | RNS | Director/PDMR Shareholding | 
                                                                            
                                            | 4th May 2020 7:00 am | RNS | Director/PDMR Shareholding | 
                                                                            
                                            | 1st May 2020 7:00 am | RNS | Board Changes | 
                                                                            
                                            | 29th Apr 2020 10:43 am | RNS | Holding(s) in Company | 
                                                                            
                                            | 27th Apr 2020 7:00 am | RNS | Full Year Unaudited Results 2019 | 
                                                                            
                                            | 17th Apr 2020 3:56 pm | RNS | Results of Placing | 
                                                                            
                                            | 17th Apr 2020 11:00 am | RNS | Proposed Placing and COVID-19 update | 
                                                                            
                                            | 3rd Apr 2020 11:35 am | RNS | Holding(s) in Company | 
                                                                            
                                            | 2nd Apr 2020 4:40 pm | RNS | Second Price Monitoring Extn | 
                                                                            
                                            | 2nd Apr 2020 4:36 pm | RNS | Price Monitoring Extension | 
                                                                            
                                            | 1st Apr 2020 10:56 am | RNS | Holdings in Company | 
                                                                            
                                            | 27th Mar 2020 7:00 am | RNS | Full Year Results Deferral and COVID-19 Update | 
                                                                            
                                            | 25th Mar 2020 11:20 am | RNS | Holding(s) in Company | 
                                                                            
                                            | 19th Mar 2020 4:43 pm | RNS | Second Price Monitoring Extn | 
                                                                            
                                            | 19th Mar 2020 4:39 pm | RNS | Price Monitoring Extension | 
                                                                            
                                            | 17th Mar 2020 12:03 pm | RNS | Price Monitoring Extension | 
                                                                            
                                            | 27th Feb 2020 10:38 am | RNS | Director/PDMR Shareholding | 
                                                                            
                                            | 26th Feb 2020 7:00 am | RNS | Presentation Cowen Annual Health Care Conference | 
                                                                            
                                            | 17th Feb 2020 7:00 am | RNS | Total Voting Rights | 
                                                                            
                                            | 14th Feb 2020 2:46 pm | RNS | Holding(s) in Company | 
                                                                            
                                            | 4th Feb 2020 7:00 am | RNS | Confidential submission of Form F-1 to SEC | 
                                                                            
                                            | 4th Feb 2020 7:00 am | RNS | Trading Update | 
                                                                            
                                            | 27th Jan 2020 1:51 pm | RNS | Block Listing Six Monthly Return | 
                                                                            
                                            | 14th Jan 2020 7:00 am | RNS | Update on Base Editing Technology License | 
                                                                            
                                            | 18th Dec 2019 7:00 am | RNS | Presentation at J.P. Morgan Healthcare Conference | 
                                                                            
                                            | 16th Dec 2019 12:07 pm | RNS | Second Price Monitoring Extn | 
                                                                            
                                            | 16th Dec 2019 12:02 pm | RNS | Price Monitoring Extension | 
                                                                            
                                            | 13th Dec 2019 7:00 am | RNS | Collaboration with Mammoth Biosciences | 
                                                                            
                                            | 4th Dec 2019 12:08 pm | RNS | Second Price Monitoring Extn | 
                                                                            
                                            | 4th Dec 2019 12:02 pm | RNS | Price Monitoring Extension | 
                                                                            
                                            | 4th Dec 2019 7:00 am | RNS | Completion of Divestment of In Vivo Business Unit | 
                                                                            
                                            | 8th Nov 2019 7:00 am | RNS | Divestment of In Vivo Business Unit | 
                                                                            
                                            | 22nd Oct 2019 3:22 pm | RNS | Additional Block Listing and Total Voting Rights | 
                                                                            
                                            | 4th Oct 2019 12:07 pm | RNS | Second Price Monitoring Extn | 
                                                                            
                                            | 4th Oct 2019 12:02 pm | RNS | Price Monitoring Extension | 
                                                                            
                                            | 19th Sep 2019 3:30 pm | RNS | Holding(s) in Company | 
                                                                            
                                            | 16th Sep 2019 7:00 am | RNS | Half-year Report | 
                                                                            
                                            | 12th Aug 2019 12:07 pm | RNS | Second Price Monitoring Extn | 
                                                                            
                                            | 12th Aug 2019 12:02 pm | RNS | Price Monitoring Extension | 
                                                                            
                                            | 26th Jul 2019 7:00 am | RNS | Block Listing Six Monthly Return |