| 14th Apr 2008 7:01 am | 
                                            RNS | 
                                            CardioQ update | 
                                        
                                                                            
                                            | 7th Apr 2008 7:01 am | 
                                            RNS | 
                                            Final Results | 
                                        
                                                                            
                                            | 7th Apr 2008 7:01 am | 
                                            RNS | 
                                            New Non-Executive Director | 
                                        
                                                                            
                                            | 3rd Apr 2008 7:00 am | 
                                            RNS | 
                                            CardioQ update | 
                                        
                                                                            
                                            | 2nd Apr 2008 7:01 am | 
                                            RNS | 
                                            CardioQ update | 
                                        
                                                                            
                                            | 28th Mar 2008 7:02 am | 
                                            RNS | 
                                            NTAH update | 
                                        
                                                                            
                                            | 26th Mar 2008 7:02 am | 
                                            RNS | 
                                            CardioQ update | 
                                        
                                                                            
                                            | 20th Mar 2008 7:00 am | 
                                            RNS | 
                                            Notice of Results | 
                                        
                                                                            
                                            | 3rd Mar 2008 3:22 pm | 
                                            RNS | 
                                            ODM meta - analysis | 
                                        
                                                                            
                                            | 25th Jan 2008 3:58 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 23rd Jan 2008 7:01 am | 
                                            RNS | 
                                            Positive Scientific Review | 
                                        
                                                                            
                                            | 23rd Jan 2008 7:01 am | 
                                            RNS | 
                                            Pre-close update | 
                                        
                                                                            
                                            | 18th Jan 2008 11:41 am | 
                                            RNS | 
                                            HSJ Article | 
                                        
                                                                            
                                            | 26th Nov 2007 9:03 am | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 21st Nov 2007 7:02 am | 
                                            RNS | 
                                            CardioQ Product Endorsement | 
                                        
                                                                            
                                            | 31st Oct 2007 2:15 pm | 
                                            RNS | 
                                            Total Voting Rights | 
                                        
                                                                            
                                            | 22nd Oct 2007 9:01 am | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 16th Oct 2007 4:03 pm | 
                                            RNS | 
                                            Additional Listing | 
                                        
                                                                            
                                            | 1st Oct 2007 7:06 am | 
                                            RNS | 
                                            CardioQ announcement | 
                                        
                                                                            
                                            | 25th Sep 2007 11:00 am | 
                                            RNS | 
                                            Interim Results - Replacement | 
                                        
                                                                            
                                            | 25th Sep 2007 7:03 am | 
                                            RNS | 
                                            Interim Results | 
                                        
                                                                            
                                            | 16th Aug 2007 3:53 pm | 
                                            RNS | 
                                            AIM Rule 26 Information | 
                                        
                                                                            
                                            | 31st Jul 2007 3:29 pm | 
                                            RNS | 
                                            Total Voting Rights | 
                                        
                                                                            
                                            | 25th Jul 2007 11:30 am | 
                                            RNS | 
                                            Recommendation for CardioQ | 
                                        
                                                                            
                                            | 11th Jul 2007 7:01 am | 
                                            RNS | 
                                            Trading Statement | 
                                        
                                                                            
                                            | 5th Jul 2007 3:30 pm | 
                                            RNS | 
                                            Improving Surgical Outcomes | 
                                        
                                                                            
                                            | 29th Jun 2007 3:34 pm | 
                                            RNS | 
                                            Director/PDMR Shareholding | 
                                        
                                                                            
                                            | 29th Jun 2007 3:26 pm | 
                                            RNS | 
                                            Additional Listing | 
                                        
                                                                            
                                            | 29th Jun 2007 8:52 am | 
                                            RNS | 
                                            Total Voting Rights | 
                                        
                                                                            
                                            | 28th Jun 2007 7:04 am | 
                                            RNS | 
                                            New Clinical Evidence | 
                                        
                                                                            
                                            | 22nd Jun 2007 7:01 am | 
                                            RNS | 
                                            Additional Listing | 
                                        
                                                                            
                                            | 19th Jun 2007 3:02 pm | 
                                            RNS | 
                                            Holding(s) in Company | 
                                        
                                                                            
                                            | 14th Jun 2007 4:02 pm | 
                                            RNS | 
                                            Additional Listing | 
                                        
                                                                            
                                            | 7th Jun 2007 7:03 am | 
                                            RNS | 
                                            New CardioQ Data | 
                                        
                                                                            
                                            | 5th Jun 2007 7:02 am | 
                                            RNS | 
                                            US Reimbursement Update | 
                                        
                                                                            
                                            | 31st May 2007 8:49 am | 
                                            RNS | 
                                            Total Voting Rights | 
                                        
                                                                            
                                            | 23rd May 2007 7:32 am | 
                                            RNS | 
                                            US Reimbursement Coverage | 
                                        
                                                                            
                                            | 22nd May 2007 8:31 am | 
                                            RNS | 
                                            Additional Listing | 
                                        
                                                                            
                                            | 3rd May 2007 1:06 pm | 
                                            RNS | 
                                            Issue of Equity | 
                                        
                                                                            
                                            | 3rd May 2007 10:25 am | 
                                            RNS | 
                                            AGM Statement |