TR-1: Notification of major interest in shares

8th Oct 2010 07:00

For filings with the FSA include the annex For filings with issuer exclude the annex

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi

1. Identity of the issuer or the underlying issuer Sinclair Pharma Plc of existing shares to which voting rights are

attached:ii Sedol 3385674

2 Reason for the notification (please tick the appropriate box or boxes): An acquisition or disposal of voting rights

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments An event changing the breakdown of voting rights

Other (please specify): Participation in placing and open offer √ ¹Lansdowne Partners Limited being the General Partner of Lansdowne Partners

3. Full name of person(s) subject to the Limited Partnership

notification obligation:iii ²Lansdowne Partners International Limited

4. Full name of shareholder(s) Morstan Nominees Ltd

(if different from 3.):iv (Registered Shareholders)

5. Date of the transaction and date on which the threshold is crossed or 06/10/2010

reached: v

6. Date on which issuer notified: 07/10/2010 7. Threshold(s) that is/are crossed or 15%, 16%

reached: vi, vii 8. Notified details:

A: Voting rights attached to shares viii, ix Class/type Situation previous Resulting situation after the triggering transactionof to the triggering shares transaction Number Number Number Number of voting % of voting rights xif possible of of of rights using Shares Voting shares the ISIN Rights CODE Direct Direct xi Indirect Direct Indirect xii Ordinary Shares 23,524,889 23,524,889 37,757,952 16.38% GB0033856740

B: Qualifying Financial Instruments Resulting situation after the triggering transaction

Type of Expiration Exercise/ Number of voting % of voting financial date xiii Conversion Period rights that may be rights instrument xiv acquired if the instrument is exercised/ converted. C: Financial Instruments with similar economic effect to Qualifying Financial Instruments xv, xvi

Resulting situation after the triggering transaction Type of Exercise price Expiration Exercise/ Number of voting rights

% of voting financial date xvii Conversion instrument refers to rights xix, xx instrument period xviii Nominal Delta Total (A+B+C) Number of voting rights Percentage of voting rights 37,757,952 16.38%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: xxi

Lansdowne Partners International Limited is the parent undertaking of Lansdowne Partners Limited. Proxy Voting: 10. Name of the proxy holder: Lansdowne Partners Limited

11. Number of voting rights proxy holder will cease

to hold:

12. Date on which proxy holder will cease to hold

voting rights: 13. Additional information: 14. Contact name: Johanna Stohr 15. Contact telephone number: +44(0)20 7290 5500

vendor

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Related Shares:

Sinclair Pharma