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Study Shows PuriCore's Aquatine(TM) EC Effective for Root Canal Disinfecting and Cleansing

21st May 2007 12:00

PuriCore (LSE: PURI), the life sciences company focused on thedevelopment and commercialization of its novel, safe antimicrobialtechnology, announced that results of a university study comparing itsendodontic cleanser, Aquatine EC (hypochlorous acid), to bleach(sodium hypochlorite) for root canal disinfecting and cleansing werepresented at the American Association of Endodontists annualconference in Philadelphia, PA. The researchers found that theAquatine EC endodontic cleanser was extremely effective atdisinfecting tooth root canals contaminated with bacteria(Enterococcus faecalis) when compared to bleach, the gold standard forendodontic disinfection. Furthermore, when used in combination withEDTA, Aquatine EC was also highly effective at removing the smearlayer. The independent study, sponsored by PuriCore, was led by DrsMurray and Garcia-Godoy and conducted by Drs Garcia, Kuttler andNamerow at Nova Southeastern University College of Dental Medicine. £ PuriCore's proprietary technology produces hypochlorous acid, thesame natural antimicrobial produced by the human body to fightpathogens, from the electrolysis of a saline solution. In 2006,PuriCore received 510(k) clearance from the US Food and DrugAdministration (FDA) allowing it to market its proprietary Aquatine ECendodontic cleanser as a medical device in the US. Aquatine ismarketed by PuriCore's Sterilox Dental division. £ Currently, bleach is commonly used as a root canal irrigant;however, it is cytotoxic and can cause severe tissue damage. Incontrast, PuriCore's Aquatine EC solution is biocompatible andconsidered safe to humans and the environment. £ About PuriCore £ PuriCore (London Stock Exchange: PURI) is a life sciences companyfocused on developing and commercializing proprietary products thatsafely, effectively, and naturally kill contagious pathogens.PuriCore's technology provides a solution to a broad range of marketsthat depend upon controlling contamination, including food safety,medical device disinfection, wound management, and hospitality. TheCompany's proprietary technology mimics the human body's production ofthe natural antimicrobial hypochlorous acid, which is highly effectivein killing bacteria, viruses, and fungal spores. Deployinghypochlorous acid solutions as soaks, sprays, mists, and in otherforms, PuriCore's technology is designed to limit the spread ofinfectious disease, including major public health threats of M.tuberculosis, MRSA, E.coli, norovirus, avian influenza, HIV, poliovirus, Helicobater pylori, and Legionella. PuriCore is headquarteredin Malvern, Pennsylvania, with offices in Stafford, UK. £ To receive additional information on PuriCore, please visit ourweb site at www.puricore.com, which does not form part of this pressrelease. Copyright Business Wire 2007

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