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Rule 8.3 - Tepnel Life Sciences Plc

7th Apr 2009 07:00

FORM 8.3 DEALINGS BY PERSONS WITH INTERESTS IN SECURITIES REPRESENTING 1% OR MORE (Rule 8.3 of the Takeover Code)

1. KEY INFORMATION

Name of person dealing (Note 1) OrbiMed Capital LLC Company dealt in Tepnel Life Sciences Plc Class of relevant security to 1p ordinary

which the dealings being disclosed relate (Note 2) Date of dealing April 3. 2009

2. INTERESTS, SHORT POSITIONS AND RIGHTS TO SUBSCRIBE

(a) Interests and short positions (following dealing) in the class of relevantsecurity dealt in (Note 3) Long Short Number (%) Number (%) (1) Relevant securities 92,840,000 28.04% (2) Derivatives (other than options) (3) Options and agreements to purchase/sell Total

(b) Interests and short positions in relevant securities of the company, other than the class dealt in (Note 3)

Class of relevant security: Long Short Number (%) Number (%) (1) Relevant securities (2) Derivatives (other than options)

(3) Options and agreements to purchase/sell Total

(c) Rights to subscribe (Note 3)

Class of relevant security: Details 3. DEALINGS (Note 4)(a) Purchases and salesPurchase/sale Number of securities Price per unit (Note 5)

(b) Derivatives transactions (other than options)

Product name, Long/short (Note Number of securities Price per unit (Note 6) (Note 7) 5) e.g. CFD

(c) Options transactions in respect of existing securities

(i) Writing, selling, purchasing or varying

Product name, Writing, Number of Exercise Type, e.g. Expiry Option

selling, securities to American, money e.g. call purchasing, which the price European date option varying option etc. paid/ etc. relates (Note received 7) per unit (Note 5) (ii) ExercisingProduct name, e.g. call Number of securities Exercise price per unit option (Note 5)

(d) Other dealings (including new securities) (Note 4)

Nature of transaction Details Price per unit (if (Note 8) applicable) (Note 5) Exercise of warrants Received 45,840,000 Exercise price of 6.98 ordinary shares pence per share 4. OTHER INFORMATION

Agreements, arrangements or understandings relating to options or derivatives

Full details of any agreement, arrangement or understanding between the person disclosing and any other person relating to the voting rights of any relevant securities under any option referred to on this form or relating to the voting rights or future acquisition or disposal of any relevant securities to which any derivative referred to on this form is referenced. If none, this should be stated.

OrbiMed Capital LLC holds investment and voting discretion over the following entities:

Finsbury Worldwide Pharmaceutical Trust plc 74,000,000 ordinary shares (22.35%) The Biotech Growth Trust plc 18,840,000 ordinary shares (5.69%)

Is a Supplemental Form 8 attached? (Note 9) NO

Date of disclosure April 6, 2009 Contact name Eric Bittelman Telephone number 212-739-6400

If a connected EFM, name of offeree/offeror N/A with which connected If a connected EFM, state nature of N/A connection (Note 10)

Notes

The Notes on Form 8.3 can be viewed on the Takeover Panel's website at www.thetakeoverpanel.org.uk

vendor

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