Rule 2.10 Announcement

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, IN, INTO OR FROM THE UNITED STATES OR ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION.

FOR IMMEDIATE RELEASE

16 March 2016

Vectura Group plc ("Vectura")

Rule 2.10 Announcement - Relevant Securities in Issue

In accordance with Rule 2.10 of the UK Takeover Code, Vectura confirms that as at the close of business on 15 March 2016 it had the following securities in issue:

· 410,530,184 ordinary shares of 0.025 pence each admitted to trading on the London Stock Exchange's main market for listed securities. The International Securities Identification Number (ISIN) for Vectura's ordinary shares is GB00B01D1K48.