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Q3 2005 Results Date Notification – Nov 3, 2005

24th Oct 2005 14:00

THIRD QUARTER 2005 RESULTS DATE NOTIFICATION - November 3, 2005Basingstoke, UK and Philadelphia, US - October 24, 2005 - Shire PharmaceuticalsGroup plc (LSE: SHP, NASDAQ: SHPGY; TSX: SHQ) will announce third quarter 2005US GAAP earnings on Thursday, November 3, 2005.Results announcement time: 12:00 GMT / 07:00 ET Conference call time: 14:00 GMT / 09:00 ET Live conference call:Matthew Emmens, Chief Executive Officer and Angus Russell, Chief FinancialOfficer will host the live conference call at 14:00 GMT/09:00 ET.Please RSVP ssalah@uk.shire.com (T: +44 (0)1256 894 160).The details of the live conference call are as follows:UK dial in +44 (0) 1452 568 061 US / Canada dial in 1866 224 2972 Password Shire Live Webcast:The call will also be available live over the Internet via audio webcast,accessible through www.shire.com in the investor relations/Events section. Aslide presentation to accompany the call will also be available on the Shirewebsite.Replay:A replay of the presentation will be available for two weeks. Details are asfollows:UK dial in 0845 245 5205 US dial in 18662474222 Stnd Int Dial In Number +44 (0) 1452 55 00 00 Pin code 1684507 # Webcast Replay www.shire.com, in the investor relations section If you have any problems accessing this, please contact: Souheil Salah on: +44(0) 1256 894160For further information please contact:Investor Relations Souheil Salah (Rest of the World) +44 1256 894 160 Heidi Wunder (North America) +1 484 595 8709 Notes to editorsShire Pharmaceuticals Group plcShire Pharmaceuticals Group plc (Shire) is a global specialty pharmaceuticalcompany with a strategic focus on meeting the needs of the specialist physicianand currently focuses on developing and marketing products in the areas ofcentral nervous system (CNS), gastrointestinal (GI), renal diseases and humangenetic therapies. Shire has operations in the world's key pharmaceuticalmarkets (US, Canada, UK, France, Italy, Spain and Germany) as well as aspecialist drug delivery unit in the US.For further information on Shire, please visit the Company's website: www.shire.com.Hampshire International Business Park Chineham Basingstoke Hampshire RG24 8EP United Kingdom Tel +44 (0)1256 894000 Fax +44 (0)1256 894708 www.shire.com Press Release Registered in England 2883758 Registered Office as aboveENDShire Pharmaceuticals Group PLC

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