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Purchase of Shares by Employee Benefit Trust

27th Sep 2006 07:00

27Sep 2006Purchase of Shares by Employee Benefit TrustShire plc ("Shire")Shire has been notified that on 26 September 2006, the Shire plc EmployeeBenefit Trust (the "Trust") purchased 135,000 Ordinary Shares of Shire plc("Shares") at an average price of 851.1400 pence per Share. This purchase wasmade pursuant to the Trustee's irrevocable, non-discretionary programme topurchase Shares during the period commencing 16th August 2006 to 30th September2006.All of the employees of Shire plc and its subsidiaries, including the ExecutiveDirectors and persons exercising managerial responsibility, are potentialbeneficiaries of the Trust. The Executive Directors and persons exercisingmanagerial responsibility over Shire are therefore deemed to have an interestin the Shares held by the Trust.For further information please contact:Investor RelationsClĩa Rosenfeld (Rest of the World) +44 1256 894 160Brian Piper (North America) +1 484 595 8252Notes to editorsSHIRE PLCShire's strategic goal is to become the leading specialty pharmaceuticalcompany that focuses on meeting the needs of the specialist physician. Shirefocuses its business on attention deficit and hyperactivity disorder (ADHD),human genetic therapies (HGT), gastrointestinal (GI) and renal diseases. Thestructure is sufficiently flexible to allow Shire to target new therapeuticareas to the extent opportunities arise through acquisitions. Shire believesthat a carefully selected portfolio of products with a strategically alignedand relatively small-scale sales force will deliver strong results.Shire's focused strategy is to develop and market products for specialtyphysicians. Shire's in-licensing, merger and acquisition efforts are focused onproducts in niche markets with strong intellectual property protection eitherin the US or Europe.For further information on Shire, please visit the Company's website:www.shire.com.ENDSHIRE PLC

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