Purchase of Shares by Employee Benefit Trust

SHIRE PLC - Purchase of Shares by Employee Benefit Trust

PR Newswire

London, May 8

Purchase of Shares by Employee Benefit Trust

May 8, 2013 - Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialtybiopharmaceutical company, announces that the Shire Employee Benefit Trust (the"Trust") has been requested to purchase up to a total of US$50 million of Shireplc American Depositary Shares (ADSs) over the period May 8, 2013 to July 31,2013.

Any such purchases will be made for the benefit of the Trust, in connectionwith Shire's management of its various employee share schemes. Any purchaseshave been requested to be made on an irrevocable, non-discretionary, rollingbasis.

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Shire enables people with life-altering conditions to lead better lives.

Our strategy is to focus on developing and marketing innovative specialtymedicines to meet significant unmet patient needs.

We provide treatments in Neuroscience, Rare Diseases, Gastrointestinal,Internal Medicine and Regenerative Medicine and we are developing treatmentsfor symptomatic conditions treated by specialist physicians in other targetedtherapeutic areas.

www.shire.com