Publication of Supplementary Prospectus

Publication of Supplementary Prospectus

The following supplementary prospectus dated 11 May 2018 has been approved by the UK Listing Authority and is available for viewing:

GlaxoSmithKline plc, GlaxoSmithKline Capital plc and GSK Capital K.K. £15,000,000,000 Euro Medium Term Note Programme

Copies of the supplementary prospectus and the documents incorporated by reference within it have been submitted to the National Storage Mechanism and will shortly be available for inspection at and can be downloaded from:

www.morningstar.co.uk/uk/NSM

For further information, please contact:

GlaxoSmithKline plc

980 Great West Road

Brentford

Middlesex

TW8 9GS

United Kingdom

Enquiries:

BASIS ON WHICH YOU MAY ACCESS THE SUPPLEMENTARY PROSPECTUS

Please note that the information contained in the supplementary prospectus may be addressed to and/or targeted at persons who are residents of particular countries (specified in the supplementary prospectus) only and is not intended for use and should not be relied upon by any person outside these countries and/or to whom the offer contained in the supplementary prospectus is not addressed. Prior to relying on the information contained in the supplementary prospectus you must ascertain from the supplementary prospectus whether or not you are part of the intended addressees of the information contained therein.

Your right to access this service is conditional upon complying with the above requirements.