Presentation at Proactiveinvestors One2One Forum

For Immediate Release 21 October 2013

Sphere Medical Holding plc

Sphere Medical to present at Proactiveinvestors One2One Investor Forum on Thursday, 24th October 2013

Cambridge, UK, 21 October 2013: Sphere Medical Holding plc (AIM: SPHR.L) ("Sphere Medical" or the "Company"), a leading developer of innovative monitoring and diagnostic products for the critical care setting, announces that Stuart Hendry, Chief Executive Officer, will be presenting at the Proactiveinvestors One2One Investor Forum on Thursday, 24th October 2013.

The event will run from 5.45pm (6.00pm start) to 8:00pm and will be held at the Chesterfield Mayfair Hotel, 35 Charles Street, Mayfair W1J 5EB in the Charles Suite (on the 1st Floor).

Further information (including a link to register participation) can be found at: http://www.proactiveinvestors.co.uk/register/event_details/207

For further information, please contact:

Sphere Medical Holding plc Tel: +44 (0)1223 875222

Dr Stuart Hendry, Chief Executive Officer

Matthew Hall, Chief Financial Officer

Peel Hunt LLP Tel: +44 (0) 20 7418 8900

James Steel

Dr Vijay Barathan

Jock Maxwell Macdonald

finnCap Tel: +44 (0) 20 7220 0500

Geoff Nash / Simon Hicks

Stephen Norcross

Consilium Strategic Communications Tel: +44 (0) 20 7920 2354

Mary-Jane Elliott [email protected]

Amber Bielecka

Matthew Neal

Notes for Editors

Sphere Medical (AIM: SPHR.L), is a medical device company developing a range of innovative monitoring and diagnostic devices designed to significantly improve patient care.

Sphere Medical's products deliver real time analysis of blood gases, electrolytes and drug levels with laboratory accuracy, at the patient's bedside. Sphere Medical's products can be used in a wide range of medical applications, enabling faster clinical decision making and improved patient outcomes, whilst reducing costs for healthcare payers.

Sphere Medical has a number of partnerships with industry leading medical device companies with strategic investments such as Ortho-Clinical Diagnostics, Inc. and Sorin Group.

For further information, please visit www.spheremedical.com