Posting of Shareholder Circular

Sphere Medical Holding plc

("Sphere Medical" or the "Company")

Posting of Shareholder Circular

Cambridge, UK, 1 July 2013: Sphere Medical Holding plc (AIM: SPHR.L), a leading developer of innovative monitoring and diagnostic products for the critical care setting, is pleased to confirm that, further to the announcement on 28 June 2013, which gave details of the Company's proposed Collaboration agreement and fundraising through a placing, subscription and open offer, it has posted the circular to shareholders. The circular contains the notice convening the General Meeting to be held at 5 New Street Square, London EC4A 3TW on 16 July 2013 at 10.00am.

A copy of the circular is available on the Company's website: www.spheremedical.com.

For further information, please contact:

About Sphere Medical

Sphere Medical (AIM: SPHR.L), is a medical device company developing a range of innovative monitoring and diagnostic devices designed to significantly improve patient care.

Sphere Medical's Proxima and Cardiopulmonary Bypass devices deliver real time analysis of blood gases, electrolytes, glucose and drug levels with laboratory accuracy, at the patient's bedside. Globally over 240 million blood gas and electrolyte tests are carried out on patients every year in critical care and there is an unmet need for monitoring products that are small, simple to use and cost effective with improved functionality. Sphere Medical's products can be used in a wide range of medical applications enabling faster clinical decision making and consequently improved patient outcomes, whilst also reducing costs for healthcare payers.

Sphere Medical is headquartered in Cambridge, UK and employs around 60 people. The Company has existing commercial partnerships with the leading global medical device companies. For further information, please visit www.spheremedical.com