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Notification of Shares

24th Jul 2007 11:07

Alizyme PLC24 July 2007 For Immediate Release 24 July 2007 ALIZYME PLC TR - 1: NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached: Alizyme plc 2. Reason for the notification (please tick the appropriate box or boxes): An acquisition or disposal of voting rights 3. Full name of person(s) subject to the notification obligation: Prudential plc group of companies 4. Full name of shareholder(s) (if different from 3.) BK OF NEW YORK(NOMS)LTD/636922 415,000 NORTRUST NOMINEE LTD A/C MHF01 43,516 NORTRUST NOMINEE LTD A/C MKK01 21,371,275 NORTRUST NOMS LTD A/C MEL01 911,274 PRUCLT HSBC GIS NOM(UK) PAC AC 2,555,036 PRUCLT HSBC GIS NOM(UK) PPL AC 3,070,548 PSIT2 US HIGH TECH FUND 66,657 5. Date of the transaction and date on which the threshold is crossed orreached: 19/07/2007 6. Date on which issuer notified: 23/07/2007 7. Threshold(s) that is/are crossed or reached: 14% 8. Notified details: A: Voting rights attached to shares Class/type Situation previous to the Resulting situation after the triggering transactionof shares Triggering transactionif possibleusing the Number of Number of Number of Number of voting % of votingISIN CODE Shares Voting Rights shares rights rights Direct Direct Indirect Direct IndirectOrdinary 27,575,188 27,575,188 28,433,306 28,433,306 14.19%SharesGB 2pGB0000374289 B: Financial Instruments Resulting situation after the triggering transactionType of Expiration Exercise/ Number of voting rights that may be % offinancial date Conversion acquired if the instrument is votinginstrument exercised/ converted. rights Period/ Daten/a n/a n/a n/a n/a Total (A+B) Number of voting rights % of voting rights 28,433,306 14.19% 9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable Prudential plc (parent Company) M&G Group Limited (wholly owned subsidiary of Prudential plc) M&G Limited (wholly owned subsidiary of M&G Group Limited) M&G Investment Management Limited (wholly owned subsidiary of M&G Limited) M&G Securities Limited (wholly owned subsidiary of M&G Limited) Proxy Voting: 10. Name of the proxy holder: n/a 11. Number of voting rights proxy holder will cease to hold: n/a 12. Date on which proxy holder will cease to hold voting rights: n/a 13. Additional information None 14. Contact name: David Campbell, Finance Director 15. Contact telephone number: + 44 (0) 1223 896000 For further information, please contact: David Campbell, Finance DirectorALIZYME plc Tel No: + 44 (0) 1223 896000 Further information on Alizyme can be found on the Company's website: www.alizyme.com This information is provided by RNS The company news service from the London Stock Exchange

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Prudential
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