Notification of Major Interests in Shares

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi

1. Identity of the issuer or the underlying issuerof existing shares to which voting rights areattached: ii

MDY HEALTHCARE PLC

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

CHANGE IN TOTAL VOTING RIGHTS ANNOUNCED BY ISSUER

YES

3. Full name of person(s) subject to thenotification obligation: iii

3i GROUP PLC (DIRECT)

3i INVESTMENTS PLC (INDIRECT)

4. Full name of shareholder(s)  (if different from 3.):iv

BNY (OCS) NOMINEES LIMITED 3i PLC ACCT

5. Date of the transaction and date onwhich the threshold is crossed orreached: v

NO TRANSACTION

6. Date on which issuer notified:

2 APRIL 2012

7. Threshold(s) that is/are crossed orreached: vi, vii

28%, 27%

8. Notified details:

A: Voting rights attached to shares viii, ix

Class/type ofshares

if possible usingthe ISIN CODE

Situation previousto the triggeringtransaction

Resulting situation after the triggering transaction

NumberofShares

NumberofVotingRights

Numberof shares

Number of votingrights

% of voting rights x

Direct xi

Indirect xii

Direct

Indirect

ORDINARY

4,865,231

4,865,231

4,865,231

4,865,231

SEE SECTION 9 BELOW

26.6114%

SEE SECTION 9 BELOW

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Expirationdate xiii

Exercise/Conversion Period xiv

Number of votingrights that may beacquired if theinstrument isexercised/ converted.

% of votingrights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments xv, xvi

Resulting situation after the triggering transaction

Type of financialinstrument

Exercise price

Expiration date xvii

Exercise/Conversion period xviii

Number of voting rights instrument refers to

% of voting rights xix, xx

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

4,865,231

26.61%

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable: xxi

BNY (OCS) NOMINEES LIMITED 3i PLC ACCT HOLDS THE SHARES AS CUSTODIAN. THE BENEFICIAL TITLE TO THE SHARES IS HELD BY 3i GROUP PLC.

3i INVESTMENTS PLC (A WHOLLY OWNED SUBSIDIARY OF 3i GROUP PLC) HAS AN INDIRECT INTEREST IN THE TOTAL NUMBER OF VOTING RIGHTS DISCLOSED IN SECTION 8 ABOVE IN ITS CAPACITY AS THE DISCRETIONARY INVESTMENT MANAGER OF 3i GROUP PLC. 3i HOLDINGS PLC AND 3i PLC ARE BOTH WHOLLY OWNED SUBSIDIARY UNDERTAKINGS OF 3i GROUP PLC AND PARENT UNDERTAKINGS OF 3i INVESTMENTS PLC.

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will ceaseto hold:

12. Date on which proxy holder will cease to holdvoting rights:

13. Additional information:

NOTIFICATION USING TOTAL VOTING RIGHTS OF 18,282,486

14. Contact name:

JACKIE HARPER

15. Contact telephone number:

020 7975 3530