Notification of Major Interest in Shares

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES

1. Identity of the issuer or the underlying issuerof existing shares to which voting rights areattached:

QUANTUM PHARMA PLC

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

X

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

3. Full name of person(s) subject to thenotification obligation:

ODDO Meriten Asset Management SAS

(on behalf of its funds)

4. Full name of shareholder(s)  (if different from 3.):

N/A

5. Date of the transaction and date onwhich the threshold is crossed orreached:

21 Sept 2017

6. Date on which issuer notified:

22 Sept 2017

7. Threshold(s) that is/are crossed orreached:

HOLDINGS EXCEED 4% THRESHOLD

8. Notified details:

A: Voting rights attached to shares

Class/type ofshares

if possible usingthe ISIN CODE

Situation previousto the triggeringtransaction

Resulting situation after the triggering transaction

NumberofShares

NumberofVotingRights

Numberof shares

Number of votingrights

% of voting rights

Direct

Direct

Indirect

Direct

Indirect

Common shares

5 096 188

5 096 188

8 290 000

8 290 000

4.90%

GB00BRTL8Q42

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Expirationdate

Exercise/Conversion Period

Number of votingrights that may beacquired if theinstrument isexercised/ converted.

% of votingrights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Exercise price

Expiration date

Exercise/Conversion period

Number of voting rights instrument refers to

% of voting rights

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

169 117 640

4.90%

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14. Contact name:

Corinne LEHR / Sophie SABRI

Email : [email protected]

15. Contact telephone number:

+(33) 1 44 51 81 38 / 85 20

Note: Annex should only be submitted to the FSA not the issuer

Annex: Notification of major interests in shares

A: Identity of the persons or legal entity subject to the notification obligation

Full name

(including legal form of legal entities)

Oddo Meriten Asset Management SAS

(Asset Management company)

Contact address

(registered office for legal entities)

12 Boulevard de la Madeleine

F-75009 Paris

Phone number & email

+(33) 1 44 51 81 38 / 85 20

[email protected]

Other useful information

(at least legal representative for legal persons)

Nicolas CHAPUT

Tanguy GOSSEIN

B: Identity of the notifier, if applicable

Full name

Contact address

Phone number & email

Other useful information

(e.g. functional relationship with the person or legal entity subject to the notification obligation)

C: Additional information

For notes on how to complete form TR-1 please see the FSA website.