Notification of Major Interest in Shares

For immediate release

31 January 2011

TR-1: Notifications of Major Interests in Shares

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Oxford BioMedica Plc

2. Reason for notification (yes/no)

An acquisition or disposal of voting rights

Yes

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify):______________

3. Full name of person(s) subject to notification obligation:

Cubana Investments Limited

4. Full name of shareholder(s) (if different from 3):

5. Date of transaction (and date on which the threshold is crossed or reached if different):

28 January 2011

6. Date on which issuer notified:

31 January 2011

7. Threshold(s) that is/are crossed or reached:

13%

8: Notified Details

A: Voting rights attached to shares

Class/type of shares

If possible use ISIN code

GB0006648157

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Number of shares

54,824,711

Number of voting rights

54,814,711

Number of shares

125,300,000

Number of voting rights

Percentage of voting rights

Direct

125,300,000

Indirect

Direct

13.26%

Indirect

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ conversion period/date

No. of voting rights that may be acquired (if the instrument exercised/converted)

Percentage of voting rights

Total (A+B)

Number of voting rights

Percentage of voting rights

125,300,000

13.26%

9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14 Contact name:

Andrew Wood

15. Contact telephone number:

01865 783000