Notification of major interest in shares

For filings with the FSA include the annex

For filings with issuer exclude the annex

TR-1: Notifications of Major Interests in Shares

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Regenersis PLC

2. Reason for notification (yes/no)

An acquisition or disposal of voting rights

YES

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

NO

An event changing the breakdown of voting rights

NO

Other (please specify):______________

N/A

3. Full name of person(s) subject to notification obligation:

IMPAX ASSET MANAGEMENT LIMITED

4. Full name of shareholder(s) (if different from 3):

Impax Environmental Markets plc, Impax Environmental Markets (Ireland) Fund,

Parvest Environmental Opportunities Fund

The Environment Agency Fund

5. Date of transaction (and date on which the threshold is crossed or reached if different):

10 September 2010

6. Date on which issuer notified:

13 September 2010

7. Threshold(s) that is/are crossed or reached:

13 %

8: Notified Details

A: Voting rights attached to shares

Class/type of shares

If possible use ISIN code

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Number of shares

Number of voting rights

Number of shares

Number of voting rights

Percentage of voting rights

Direct

Indirect

Direct

Indirect

Ordinary Shares

BBG000DN20X5

5,768,014

12.87%

6,018,014

NIL

6,018,014

NIL

13.43%

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ conversion period/date

No. of voting rights that may be acquired (if the instrument exercised/converted)

Percentage of voting rights

NIL

Total (A+B)

Number of voting rights

Percentage of voting rights

6,018,014

13.43%

9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable:

Impax Environmental Markets plc (3,346,814 shares 7.47%)

Impax Environmental Markets (Ireland) Fund (1,730,000 shares 3.86%)

Parvest Environmental Opportunities Fund (491,200 shares 1.10%)

The Environmental Agency Fund (6,018,014 shares 1.00%)

Proxy Voting:

10. Name of proxy holder:

N/A

11. Number of voting rights proxy holder will cease to hold:

N/A

12. Date on which proxy holder will cease to hold voting rights:

N/A

13. Additional information:

14 Contact name:

Compliance Officer

15. Contact telephone name:

+44 (0) 20 7434 1122

Annex: Notification of major interests in shares

A: Identity of the persons or legal entity subject to the notification obligation

Full name

(including legal form of legal entities)

Impax Asset Management Limited

Contact address

(registered office for legal entities)

Mezzanine Floor

Pegasus House

37-43 Sackville Street

London

W1S 3EH

Phone number & email

+44 (0) 20 7434 1122

[email protected]

Other useful information

(at least legal representative for legal persons)

B: Identity of the notifier, if applicable

Full name

Impax Operations Department

Contact address

Mezzanine Floor

Pegasus House

37-43 Sackville Street

London

W1S 3EH

Phone number & email

+44 (0) 20 7434 1122

[email protected]

Other useful information

(e.g. functional relationship with the person or legal entity subject to the notification obligation)

C: Additional information