Notification of Major Interest in Shares

For immediate release

20 September 2012

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES

1. Identity of the issuer or the underlying issuerof existing shares to which voting rights areattached:

Futura Medical plc

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

ü

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

3. Full name of person(s) subject to thenotification obligation:

Octopus Investments Nominees Limited

4. Full name of shareholder(s)

 (if different from 3.):

n/a

5. Date of the transaction and date on

which the threshold is crossed or

reached:

14/09/2012

6. Date on which issuer notified:

20/09/2012

7. Threshold(s) that is/are crossed or

reached:

3, 4%

8. Notified details: n/a

A: Voting rights attached to shares

Class/type ofshares

if possible usingthe ISIN CODE

Situation previousto the triggeringtransaction

Resulting situation after the triggering transaction

NumberofShares

NumberofVotingRights

Numberof shares

Number of votingrights

% of voting rights

Direct

Direct

Indirect

Direct

Indirect

GB0033278473

706000

706000

3398254

3398254

4.39

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial

instrument

Expiration

date

Exercise/

Conversion Period

Number of voting

rights that may be

acquired if the

instrument is

exercised/ converted.

% of voting

rights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial

instrument

Exercise price

Expiration date

Exercise/

Conversion period

Number of voting rights instrument refers to

% of voting rights

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

3398254

4.39

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable:

n/a

Proxy Voting:

10. Name of the proxy holder:

n/a

11. Number of voting rights proxy holder will cease to hold:

n/a

12. Date on which proxy holder will cease to hold voting rights:

n/a

13. Additional information:

14. Contact name:

Luke Kennedy

15. Contact telephone number:

020 7710 6462