Notification of major interest in shares

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

MedicX Fund Limited

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

Placing

ü

3. Full name of person(s) subject to the notification obligation:

 Rathbone Brothers PLC

4. Full name of shareholder(s) (if different from 3.):

Rathbone Brothers PLC

Rathbone Investment Management Ltd

Rathbones Investment Management International Ltd

5. Date of the transaction and date on which the threshold is crossed or reached:

2 March 2011

6. Date on which issuer notified:

14 March 2011

7. Threshold(s) that is/are crossed or reached:

5%

8. Notified details:

A: Voting rights attached to shares

Class/type ofshares

if possible usingthe ISIN CODE

Situation previousto the triggeringtransaction

Resulting situation after the triggering transaction

NumberofShares

NumberofVotingRights

Numberof shares

Number of votingrights

% of voting rights

Direct

Direct

Indirect

Direct

Indirect

Ordinary NPV

8,235,242

8,235,242

N/A

N/A

8,466,765

N/A

4.45%

GG00B1DVQL92

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Expirationdate

Exercise/ConversionPeriod

Number of votingrights that may beacquired if theinstrument isexercised/ converted.

% of votingrights

 N/A

N/A

N/A

N/A

N/A

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Exerciseprice

Expirationdate

Exercise/Conversionperiod

Number of votingrights instrumentrefers to

% of voting rights

 N/A

 N/A

 N/A

 N/A

 N/A

Nominal

Delta

N/A

Total (A+B+C)

Number of voting rights

Percentage of voting rights

8,466,765

4.45%

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable:

Rathbone Brothers PLC*

Rathbone Investment Management Limited 4.41%

Rathbone Investment Management International Limited 0.04%

*Rathbone Brothers Plc is the holding company of the following.

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

Total shares in Issue used as a denominator is

190,216,144

14. Contact name:

Compliance Department

15. Contact telephone number:

020 7399 0000