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Notification of a Major Interest in Shares

28th Oct 2010 11:30

SPH.L TR-1: Notification of a Major Interest in Shares

1. Identity of the issuer or the underlying SINCLAIR PHARMA PLC issuer of existing shares to which voting rights

are attached:

2. Reason for the notification (please tick the appropriate box or boxes) An acquisition or disposal of voting rights X An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights

are attached

An event changing the breakdown of voting rights

Other (please specify): 3. Full name of person(s) subject to the AXA S.A, 25 Avenue Matignon, notification obligation: 75008 Paris and its group of companies

4. Full name of shareholder(s) (if different

from 3.):

5. Date of the transaction (and date on which 26/10/2010 the threshold is crossed or reached if

different):

6. Date on which issuer notified: 27/10/2010 7. Threshold(s) that is/are crossed or reached: 10% 8. Notified details: A: Voting rights attached to shares Class/type Situation previous to Resulting situation after the triggeringof shares the triggering transaction transaction Number of Number of Number Number of voting % of voting Shares Voting of rights rights Rights shares Direct Direct Indirect Direct Indirect

3385674 22,791,411 22,791,411 0 0 23,196,411 0.00 10.07

B: Financial Instruments

Resulting situation after the triggering transaction

Type of Expiration Exercise/ Number of voting % of voting financial date Conversion rights that may be rights instrument Period/ Date acquired if the instrument is exercised/ converted. Total (A+B) Number of voting rights % of voting rights 23,196,411 10.07% 9. Chain Name of the Company / Fund Number of Shares % of issued share capital AXA IM UK 23,196,411.00 10.065332 Indirect Total Direct 0 0.00000 Total Indirect 23,196,411 10.06533 TOTAL 23,196,411 10.06533 Proxy Voting:

10. Name of the proxy holder: 11. Number of voting rights proxy holder will

cease to hold:

12. Date on which proxy holder will cease to hold

voting rights: 13. Additional information: 14. Contact name: Charles Tissier

15. Contact telephone number: 020 7003 2823

vendor

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