Notifiable share interest in JCR Pharmaceuticals

Notifiable Share Interest in JCR Pharmaceuticals Co., Limited

GlaxoSmithKline plc ("GSK") announces that, on 26 March 2010, GSK exercised stock acquisition rights at an exercise price of JPY650 per share to acquire 1,560,000 Common shares of JCR Pharmaceuticals Co., Limited ("JCR"), a pharmaceutical company located in Japan and whose shares are traded on the Osaka Stock Exchange. The details of this transaction have been disclosed in an announcement issued by JCR to the Osaka Stock Exchange on 26 March 2010.

Following this transaction, GSK's interest, which is held by its wholly owned subsidiary, Glaxo Group Limited, has increased from 12.05% to 16.73% of the outstanding Common shares of JCR, making GSK the largest shareholder of JCR. GSK's total holding represents 16.92% of the total voting rights in JCR. The details of this transaction have been disclosed in an announcement issued by JCR to the Osaka Stock Exchange on 26 March 2010.

Simon M Bicknell

Company Secretary

26 March 2010