Notifiable Interest

14th May 2007 11:40

Proteome Sciences PLC ("the Company") Notifiable Interest

A form TR-1 containing the following information has been received by the Company.

TR-1 notification of major interests in shares

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Proteome Sciences plc

2. Reason for the notification

An acquisition or disposal of voting rights

3. Full name of person(s) subject to the notification obligation:

Credit Agricole Cheuvreux International Ltd

4. Full name of shareholder(s) (if different from 3):

5. Date of the transaction (and date on which the threshold is crossed or reached if different):

09/05/07

6. Date on which issuer notified:

11/05/07

7. Threshold(s) that is/are crossed or reached:

Holding after transaction went through percentage threshold.

8. Notified details:

A: Voting rights attached to shares

Class/type Situation previous to Resulting situation after the triggering of shares Triggering transaction transaction if possible Notification required under DTR transitionalusing ISIN provision 7 CODE Number of Number of Number of Number of voting % of voting Shares Voting shares rights rights Rights Direct Direct Indirect Direct Indirect

GB0003104196 9,155,299 9,155,299 9,206,199 9,206,199 7.00%

B: Financial Instruments

Resulting situation after the triggering transaction Type of Expiration Exercise/ Number of voting rights that may % of financial date Conversion be acquired if the instrument is voting instrument Period/ Date exercised/ converted rights Total (A+B)

Number of voting rights % of voting rights

9,206,199 7.00%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:

SAS Rue La BoĩtieCrĩdit Agricole SACalyon SACrĩdit Agricole Cheuvreux SA 9,206,1990 7.00%10. Name of the Proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

PROTEOME SCIENCES PLC

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Related Shares:

Proteome