Notice of Major Interest in Shares

For immediate release

3 December 2010

1. Identity of the issuer or the underlying issuerof existing shares to which voting rights areattached:

Alliance Pharma

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

YES

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

Correction to CFD position in relation TR1 submitted 11/11/10 at 14:59

3. Full name of person(s) subject to thenotification obligation:

Old Mutual Asset Managers (UK) Ltd

4. Full name of shareholder(s)  (if different from 3.):

5. Date of the transaction and date onwhich the threshold is crossed orreached:

02nd December 2010

6. Date on which issuer notified:

03rd December 2010

7. Threshold(s) that is/are crossed orreached:

5%

8. Notified details:

A: Voting rights attached to shares

Class/type ofshares

if possible usingthe ISIN CODE

Situation previousto the triggeringtransaction

Resulting situation after the triggering transaction

NumberofShares

NumberofVotingRights

Numberof shares

Number of votingrights

% of voting rights

Direct

Direct

Indirect

Direct

Indirect

GB0031030819

8,788,920

8,788,920

7,488,920

7,488,920

3.15%

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Expirationdate

Exercise/Conversion Period

Number of votingrights that may beacquired if theinstrument isexercised/ converted.

% of votingrights

CFD

3,205,380

1.35%

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Exercise price

Expiration date

Exercise/Conversion period

Number of voting rights instrument refers to

% of voting rights

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

10,694,300

4.50%

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will ceaseto hold:

12. Date on which proxy holder will cease to holdvoting rights:

13. Additional information:

14. Contact name:

Nusrat Ghani

15. Contact telephone number:

020 7332 7504

Note: Annex should only be submitted to the FSA not the issuer

Annex: Notification of major interests in share

A: Identity of the persons or legal entity subject to the notification obligation

Full name

(including legal form of legal entities)

Old Mutual Asset Managers (UK) Ltd

Contact address

(registered office for legal entities)

2 Lambeth Hill, London, EC4P 4WR

Phone number & email

[email protected]

020 7332 7504

Other useful information

(at least legal representative for legal persons)

B: Identity of the notifier, if applicable

Full name

Nusrat Ghani

Contact address

2 Lambeth Hill, London, EC4P 4WR

Phone number & email

[email protected]

020 7332 7504

Other useful information

(e.g. functional relationship with the person or legal entity subject to the notification obligation)

C: Additional information

For notes on how to complete form TR-1 please see the FSA website.