Notice of EGM

FOR IMMEDIATE RELEASE

28 November 2012

SkyePharma PLC - Notice of General Meeting

In accordance with the Listing Rules, copies of the following documents have been submitted to the National Storage Mechanism:

·; Notice of General Meeting

·; Form of Proxy

These documents will shortly be available for inspection at the National Storage Mechanism at www.hemscott.com/nsm.do

The Notice of General Meeting is also available on the Company website at www.skyepharma.com.

The General Meeting will be held at 10.30 a.m. on Friday 21 December 2012 at the offices of FTI Consulting, Holborn Gate, 26 Southampton Buildings, London, WC2A 1PB.

For further information please contact:

SkyePharma PLC

Peter Grant, Chief Executive Officer +44 207 881 0524

Financial Dynamics

Jonathan Birt /Sue Stewart +44 207 831 3113

About SkyePharma PLC

Using its multiple drug delivery technologies and expertise, SkyePharma creates enhanced versions of pharmaceutical products. The Group receives revenues from thirteen approved products in the areas of inhalation, oral, topical and injectable delivery as well as generating income from the development of further products and technology licenses. The Group's products are marketed throughout the world by leading pharmaceutical companies. For more information, visit www.skyepharma.com.