Notice of AGM

Syncona Limited

Publication of 2025 Annual Report and Notice of Annual General Meeting

2 July 2025

Syncona Ltd, a leading life science investor, today announces that it has published its Annual Report and Accounts for the year ended 31 March 2025 ("2025 Annual Report") and its Notice of the Annual General Meeting 2025.

In compliance with Listing Rule 6.4.1, these documents will today be filed with the National Storage Mechanism and will shortly be available for inspection at https://data.fca.org.uk/#/nsm/nationalstoragemechanism

The Notice of the Annual General Meeting 2025 is available on Syncona's website at https://www.synconaltd.com/investors/shareholder-information/shareholder-documents/. The 2025 Annual Report is available on Syncona's website at https://www.synconaltd.com/investors/results-and-presentations/. Printed copies of these documents are also being posted to shareholders where requested.

Syncona's Annual General Meeting will be held at 1.00 p.m. on 5 August 2025 at the offices of Citco Fund Services (Guernsey) Limited, Frances House, Sir William Place, St. Peter Port, Guernsey, GY1 1GX.

Shareholders are encouraged to ensure that their votes are counted at the 2025 Annual General Meeting by appointing the chair of the 2025 Annual General Meeting as their proxy in line with the procedures set out in the Notice of Annual General Meeting.

If the proposals the Board outlined in the Strategy Update published on 19 June continue to progress to a conclusion, a separate general meeting will be convened to seek shareholder approval, at a date and time that will be notified to shareholders.

Enquiries

Syncona LimitedAnnabel Clark

Tel: +44 (0) 20 3981 7940

FTI Consulting

Ben Atwell / Natalie Garland-Collins

Tel: +44 (0) 20 3727 1000