New Debt Facility

Amphion Innovations plc

New Debt Facility

London and New York, 9 December 2010- Amphion Innovations plc (LSE: AMP) ("Amphion" or the "Company"), the developer of medical and technology businesses, today announces it has secured additional unsecured loan financing of $500,000 from R. James Macaleer, a director of Amphion, who is interested in 17.12% of the issued share capital of the Company. The loan is repayable on 31 January 2012 and carries interest at 5% per annum. This transaction is deemed a related party transaction for the purposes of the AIM Rules. As a result, the Independent Directors consider, having consulted with the Company's nominated adviser, that the terms of the loan are fair and reasonable insofar as its shareholders are concerned.

For further information please contact:

Amphion Innovations plc

Charlie Morgan +44 779 953 6043

Cardew Group

Tim Robertson / Jamie Milton +44 20 7930 0777

Charles Stanley (Nominated Adviser)

Mark Taylor +44 20 7149 6000

About Amphion Innovations plc

Amphion (LSE: AMP) builds shareholder value in high growth companies in the medical and technology sectors, by using a focused, hands-on company building approach, based on decades of experience in both the US and UK. Amphion has significant shareholding in 8 Partner Companies developing proven technologies targeting substantial commercial marketplaces, each in excess of $1 billion. Each Partner Company is chosen with the goal of achieving an exit valuation in excess of $100 million. The Amphion model has been refined to optimise the commercialisation of patents and other intellectual property within the Partner Companies. The Partner Companies collectively own or control over 200 separately identified pieces of intellectual property, a number that grows rapidly each year.

On the web: www.amphionplc.com