Net Asset Value(s)

POLAR CAPITAL GLOBAL HEALTHCARE TRUST PLC ("the Company")

Legal Entity Identifier: 549300YV7J2TWLE7PV84

1 December 2025

Continuing Shareholders - Net Asset Value

As at the close of business on 28 November 2025 the Company's unaudited net asset value per ordinary share, calculated in accordance with the guidelines of the Association of Investment Companies, was 427.62p (cum income). For the avoidance of doubt, this net asset value per ordinary share has been calculated on the basis of total voting rights of 94,016,974, being the estimated issued share capital (excluding shares held in treasury) following completion of the Tender Offer.

Tendering Shareholders - Tender Price

As announced earlier on 1 December 2025, the Tender Price per ordinary share tendered is 425.61p, being equal to the prevailing net asset value per ordinary share as at the close of business on 27 November 2025 less the Tender Offer Expenses per share.

In accordance with the terms of the Tender Offer, 27,253,026 ordinary shares will be purchased by Panmure Liberum Limited on or around 2 December 2025 and all such shares will then be repurchased by the Company pursuant to the Repurchase Agreement, and placed into treasury.

Capitalised terms used, but not defined, in this announcement have the same meaning as given in the Circular dated 22 October 2025.

- ENDS -

For further information, please call:

Elona Gega (Investment Trust Operations Department) 

Tracey Lago/Jumoke Kupoluyi (Polar Capital Secretarial Services)

Polar Capital Partners Limited

Tel: 020 7227 2700

http://www.polarcapitalglobalhealthcaretrust.co.uk