Migration of Shares

10 May 2012

TYRATECH, INC.

("TyraTech" or the "Company")

Migration of Shares

TyraTech, Inc. (AIM: TYR), a natural life sciences company, announces that certain of its common shares of US$0.001 in the Company ("Common Shares"), which trade on the Company's restricted trading line under TIDM 'TYR' with ISIN number USU890581080, may now be eligible to migrate to the Company's unrestricted trading line under TIDM 'TYRU' with ISIN number US90239R2031.

Removal of the trading restrictions allows the shares to be:

·; transferred to its unrestricted trading line (TIDM: TYRU); and

·; settled, by means of Depositary Interests, through the CREST electronic settlement system.

TyraTech currently has a total of 107,607,255 Common Shares in issue, of which 95,814,933 trade under TIDM 'TYR' in a restricted manner as permitted by Regulation S promulgated under the U.S. Securities Act of 1933 (as amended). The Company's remaining 11,792,322 Common Shares in issue are unrestricted and trade under TIDM 'TYRU'. TyraTech believe that approximately 26.5 million of its Common Shares are currently eligible to migrate to the unrestricted line of shares.

In general under U.S. securities law, Common Shares that have been in issue for more than one year and are not held by an 'affiliate' of the Company qualify for characterisation as unrestricted Common Shares ("Unrestricted Common Shares"). An affiliate for this purpose is a person that directly, or indirectly through one or more intermediaries, controls, or is controlled by, or is under common control with, the Company or a director or officer of the Company. Generally a beneficial owner of 10% of more of the issued Common Shares taking into account shares held and any options exercisable within 60 days will be considered an affiliate for this purpose.

All Unrestricted Common Shares are eligible for migration to, and trading on, the Company's unrestricted TYRU line.

All Common Shares not meeting the definition of Unrestricted Common Shares will continue to trade in a restricted manner under the Company's TYR line. There is no difference in entitlement between the Common Shares trading in the restricted line and those trading in the unrestricted line, but the TYRU line will serve to evidence the absence of restrictions on trading otherwise imposed by the U.S. Securities Act of 1933 (as amended) and will enable electronic settlement if a holder so desires.

The Company has sent letters with instructions to shareholders whose Common Shares it believes should be eligible for migration ("Eligible Shares") to the Company's unrestricted TYRU line.

To participate, holders of Eligible Shares must deliver their current restricted share certificates to the Company's transfer agent (Computershare Investor Services (Jersey) Limited, Queensway House, Hilgrove Street, St Helier, Jersey, JE1 1ES) together with the Letter of Transmittal which has also been sent to holders of Eligible Shares, by 8 June 2012. Holders of Eligible Shares will have the option to either receive an unrestricted certificate in return or have their Eligible Shares entered into CREST, which is a depositary interest facility that permits trading on the unrestricted TYRU line to be settled electronically. 

Shareholders in the Company who already hold unrestricted paper certificates can apply to have their certificates entered into CREST by completing a dematerialisation form and sending it to Computershare.

Copies of the letter to shareholders and the Letter of Transmittal (for eligible shareholders with restricted shares) and dematerialisation forms (for shareholders with unrestricted paper shares who wish to transfer to CREST) are available at www.tyratech.com.

For further information please contact:

TyraTech Inc.

Alan Reade, Executive Chairman Tel: +1 919 415 4310

Peter Jerome, Chief Financial Officer Tel: +1 919 415 4280

N+1 Brewin, Nominated Adviser and Joint Broker

Aubrey Powell / Robert Beenstock Tel: +44 20 3201 3170

First Columbus LLP, Joint Broker

Chris Crawford Tel: +44 20 3002 2070