Migration of shares

TYRATECH, INC.

("TyraTech" or "the Company")

Migration of Shares7 October 2011

TyraTech, Inc. (AIM: TYR), a natural life sciences company announces that certain of its shares, including shares issued pursuant to a placing in May 2010 may now be eligible to have US trading restrictions removed.

Removal of trading restrictions allows the shares to be:

·; transferred to a new unrestricted trading line (AIM: TYRU);

·; settled, by means of Depositary Interests, through the CREST electronic settlement system; and

·; sold in the US if the holders elect.

TyraTech currently has a total of 51,837,468 Common Shares of which 51,124,400 are admitted to AIM and trading under the symbol TYR in a restricted manner as permitted by Regulation S of the U.S. Securities Act of 1933 (the 'Securities Act'). Common Shares that have been in issue for more than one year and are not held by 'Affiliates' generally qualify for characterisation as 'Unrestricted Common Shares' under an exemption provided by Rule 144(k) of the Securities Act. All Unrestricted Common Shares are eligible for migration to, and trading on, the unrestricted TYRU line. All shares not meeting the definition of Unrestricted Common Shares will continue to trade in a restricted manner under the TYR line. There is no difference in entitlement between the Common Shares trading in the restricted line and those trading in the unrestricted line, but the TYRU line will serve to evidence the absence of restrictions on trading otherwise imposed by the Securities Act and will enable electronic settlement if a holder so desires. For the purposes hereof, an 'Affiliate' refers to a person that directly, or indirectly through one or more intermediaries, controls, or is controlled by, or is under common control with, the Company (e.g., a director, officer, or beneficial owner of 10% of more of the issued common shares taking into account shares held and any options exercisable within 60 days).

The Company has sent letters to shareholders whose shares it believes should be eligible with instructions for migrating those shares to the TYRU line. To participate, holders of eligible shares must deliver their current restricted share certificates to the Company's transfer agent (Computershare - Jersey) together with the Letter of Transmittal provided to them by 21 October 2011 and will have the option to either receive an unrestricted certificate in return or have their shares entered into CREST, which is a depositary interest facility that permits trading on the unrestricted TYRU line to be settled electronically.

Shareholders who already hold unrestricted paper certificates can apply to have their certificates entered into CREST by completing a dematerialisation form and sending it to Computershare.

Copies of the letter to shareholders and the Letter of Transmittal (for eligible shareholders with restricted shares) and dematerialisation forms (for shareholders with unrestricted paper shares who wish to transfer to CREST) are available at http://www.tyratech.com/content/investors/shareholder.asp.

For further information please contact:

TyraTech Inc.

Alan Reade, Executive Chairman

Tel: +1 919 415 4310

Peter Jerome, Chief Financial Officer

Tel: +1 919 415 4280

Brewin Dolphin Limited, Nominated Advisor

Matthew Davis

Tel: +44 207 248 4400