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Major Interest in Shares

12th Dec 2006 11:51

Alizyme PLC12 December 2006 For Immediate Release 12 December 2006 SCHEDULE 10 NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Name of listed company Alizyme plc 2. Name of shareholder with a major interest Prudential plc and certain of its subsidiary companies, including M&G GroupLimited, M&G Investment Management Limited, M&G Limited, M&G Securities Limitedand M&G Investment Funds (3) 3. Please state whether notification indicates that it is regarding the holdingof the shareholder named in 2 above; in respect of a non-beneficial interest; orin the case of an individual holder if it is a holding of that person's spouseor children under the age of 18 Shareholders named in 2 above 4. Name of the registered holder(s) and, if more than one holder, the number ofshares held by each of them Registered Holder Holding % BANK OF NEW YORK (NOMS) LTD/636922 415,000NORTRUST NOMINEE LTD A/C MHF01 43,516NORTRUST NOMINEE LTD A/C MKK01 20,371,275NORTRUST NOMS LTD A/C MEL01 911,274PRUCLT HSBC GIS NOM (UK) PAC AC 2,555,036PRUCLT HSBC GIS NOM (UK) PPL AC 2,820,548PSIT2 US HIGH TECH FUND 82,000 Total Notifiable Interest 27,198,649 13.63 5. Number of shares / amount of stock acquired Not disclosed 6. Percentage of issued class Not disclosed 7. Number of shares / amount of stock disposed Not applicable 8. Percentage of issued class Not applicable 9. Class of security Ordinary shares of 2p each 10. Date of transaction Not disclosed 11. Date listed company informed 12 December 2006 12. Total holding following this notification 27,198,649 13. Total percentage holding of issued class following this notification 13.63% 14. Any additional information Not applicable 15. Name of contact and telephone number for queries David CampbellTel. No. +44 (0)1223 896000 16. Name and signature of duly authorised officer of the listed companyresponsible for making this notification David Campbell, Finance Director Date of notification 12 December 2006 The FSA does not give any express or implied warranty as to the accuracy of thisdocument or material and does not accept any liability for error or omission.The FSA is not liable for any damages (including, without limitation, damagesfor loss of business or loss of profits) arising in contract, tort or otherwisefrom the use of or inability to use this document, or any material contained init, or from any action or decision taken as a result of using this document orany such material. This information is provided by RNS The company news service from the London Stock Exchange

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