Major Interest in Shares

8th Jan 2007 18:13

Protherics PLC08 January 2007 Protherics PLC Notification of Major Interest in Shares London, UK; Brentwood, TN, US; 8 January 2007 - Protherics PLC ("Protherics" orthe "Company"), the international biopharmaceutical company focused on criticalcare and cancer, announces that notification was received today from Aviva plcthat, following the purchase of 3,738,187 Ordinary 2p shares in Protherics on 4January 2007 (1.10% of the Company's issued share capital), Aviva plc and itssubsidiaries hold an interest in 40,095,830 Ordinary Shares (11.83%). The shares are represented by a beneficial interest in 20,220,671 OrdinaryShares (5.97%) and a non-beneficial interest in 19,875,159 Ordinary Shares(5.86%). This notification follows the Company's recent Placing and Open Offer and isbased on an enlarged share capital of 338,976,174 Ordinary Shares. | Ends | For further information please contact: ProthericsNick Staples, Director of Corporate Affairs +44 (0) 7919 480510Julie Vickers, Company Secretary +44 (0)1928 518010 Financial Dynamics - press enquiriesLondon: Ben Atwell, Anna Keeble +44 (0) 20 7831 3113New York: John Capodanno, Jonathan Birt +1 212 850 5600 Or visit www.protherics.com This information is provided by RNS The company news service from the London Stock Exchange

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