Launch of US version of Beating the Blues

6 October 2011

Ultrasis plc

("Ultrasis" or the "Company")

Launch of US version of Beating the Blues

Ultrasis, the leading provider of cognitive behavioural therapy for stress and mild depression delivered by computer, is pleased to announce the formal launch of U Squared Interactive LLC ("U²"), its 50:50-owned joint-venture with UPMC Insurance Services, which will be used to launch the US-specific version of "Beating the Blues" ("BtB US") to the American market.

In addition, Ultrasis is pleased to announce the completion of the development BtB US which will be marketed in the US via U², and for which U² is currently in ongoing discussions with a number of interested parties.

For further details, please visit: www.U2interactive.com and www.beatingthebluesus.com.

As previously announced on 27 February 2011, both Ultrasis and UPMC will invest to develop and drive sales opportunities across US states, government bodies, insurers, primary care providers, major corporations and other health care providers, who seek to enhance their mental health and well-being services.

-ENDS-

For further information contact:

Chris Lawrance

Editors Notes:

About Ultrasis

Ultrasis is a healthcare company with core expertise in health, psychology, software development and programme management. The Company delivers computerised healthcare products to the NHS, the corporate sector and other healthcare providers in the UK and internationally.

Ultrasis was the first company to offer computerised products based on Cognitive Behavioural Therapy ("CBT") and interactive multimedia and is the world leader in this field. The products help people tackle stress, anxiety and depression, and a full spectrum of related chronic conditions.

Beating the Blues is an eight-week, web-based treatment programme for mild and moderate depression based on CBT.

Following a rigorous examination by the National Institute for Health and Clinical Excellence ("NICE"), Beating the Blues was approved by NICE in February 2006 for use in the National Health Service.

For more information on Ultrasis please visit www.ultrasis.com.