HORIZON THERAPEUTICS PLC

FORM 8.3

IRISH TAKEOVER PANEL

DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997,

TAKEOVER RULES, 2007 (AS AMENDED)

DEALINGS BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES

REPRESENTING 1% OR MORE

1.

KEY INFORMATION

Name of person dealing (Note 1)

Barclays PLC.

Company dealt in

HORIZON THERAPEUTICS PLC

Class of relevant security to which the dealings being disclosed relate (Note 2)

$0.0001 ordinary shares

Date of dealing

10 May 2023

2.

INTERESTS AND SHORT POSITIONS

(a)

Interests and short positions (following dealing) in the class of relevant security dealt in (Note 3)

Class of relevant security:

$0.0001 ordinary shares

Long

Short

Number

(%)

Number

(%)

(1)

Relevant securities 

1,316,623

0.58%

511,915

0.22%

(2)

Derivatives (other than options):

53,580

0.02%

0

0.00%

(3)

Options and agreements to purchase/sell:

1,532,700

0.67%

1,379,500

0.60%

TOTAL:

2,902,903

1.27%

1,891,415

0.83%

(b)

Interests and short positions in relevant securities of the company, other than the class dealt in

Class of relevant security:

Long

Short

Number

(%)

Number

(%)

(1)

Relevant securities

(2)

Derivatives (other than options):

(3)

Options and agreements to purchase/sell:

TOTAL:

3.

DEALINGS (Note 4)

(a)

Purchase and sales

Class of relevant Security

Purchase/sale

Number of securities

Price per unit

$0.0001 ordinary shares

Purchase

65

110.4547 USD

$0.0001 ordinary shares

Purchase

100

110.6200 USD

$0.0001 ordinary shares

Purchase

100

110.6181 USD

$0.0001 ordinary shares

Purchase

114

110.6782 USD

$0.0001 ordinary shares

Purchase

174

110.8390 USD

$0.0001 ordinary shares

Purchase

200

110.8000 USD

$0.0001 ordinary shares

Purchase

200

110.6500 USD

$0.0001 ordinary shares

Purchase

214

110.6553 USD

$0.0001 ordinary shares

Purchase

231

110.5142 USD

$0.0001 ordinary shares

Purchase

242

110.2958 USD

$0.0001 ordinary shares

Purchase

360

110.7694 USD

$0.0001 ordinary shares

Purchase

400

110.8586 USD

$0.0001 ordinary shares

Purchase

400

110.9850 USD

$0.0001 ordinary shares

Purchase

459

110.7327 USD

$0.0001 ordinary shares

Purchase

464

110.6190 USD

$0.0001 ordinary shares

Purchase

500

110.8500 USD

$0.0001 ordinary shares

Purchase

992

110.5703 USD

$0.0001 ordinary shares

Purchase

1,140

110.5342 USD

$0.0001 ordinary shares

Purchase

1,707

110.6849 USD

$0.0001 ordinary shares

Purchase

2,856

110.5229 USD

$0.0001 ordinary shares

Purchase

3,106

110.7669 USD

$0.0001 ordinary shares

Purchase

3,310

110.5327 USD

$0.0001 ordinary shares

Purchase

3,414

110.6498 USD

$0.0001 ordinary shares

Purchase

3,549

110.6103 USD

$0.0001 ordinary shares

Purchase

5,249

110.4000 USD

$0.0001 ordinary shares

Purchase

6,252

110.4728 USD

$0.0001 ordinary shares

Purchase

8,552

110.6041 USD

$0.0001 ordinary shares

Purchase

8,815

110.8389 USD

$0.0001 ordinary shares

Purchase

9,651

110.4473 USD

$0.0001 ordinary shares

Purchase

10,157

110.4183 USD

$0.0001 ordinary shares

Purchase

11,920

110.3055 USD

$0.0001 ordinary shares

Purchase

14,450

110.4780 USD

$0.0001 ordinary shares

Purchase

15,964

110.9305 USD

$0.0001 ordinary shares

Purchase

17,348

110.6692 USD

$0.0001 ordinary shares

Purchase

20,422

110.4414 USD

$0.0001 ordinary shares

Purchase

25,000

110.7500 USD

$0.0001 ordinary shares

Purchase

31,500

110.7587 USD

$0.0001 ordinary shares

Purchase

43,624

110.5365 USD

$0.0001 ordinary shares

Purchase

50,834

110.6463 USD

$0.0001 ordinary shares

Purchase

54,051

110.6220 USD

$0.0001 ordinary shares

Purchase

68,000

110.6917 USD

$0.0001 ordinary shares

Sale

1

110.5350 USD

$0.0001 ordinary shares

Sale

2

110.0500 USD

$0.0001 ordinary shares

Sale

5

110.9300 USD

$0.0001 ordinary shares

Sale

36

110.3358 USD

$0.0001 ordinary shares

Sale

62

110.6328 USD

$0.0001 ordinary shares

Sale

100

110.2600 USD

$0.0001 ordinary shares

Sale

100

110.4900 USD

$0.0001 ordinary shares

Sale

100

110.9700 USD

$0.0001 ordinary shares

Sale

100

110.5108 USD

$0.0001 ordinary shares

Sale

100

110.7700 USD

$0.0001 ordinary shares

Sale

101

110.9199 USD

$0.0001 ordinary shares

Sale

103

110.9202 USD

$0.0001 ordinary shares

Sale

110

110.9200 USD

$0.0001 ordinary shares

Sale

111

110.7400 USD

$0.0001 ordinary shares

Sale

199

110.6947 USD

$0.0001 ordinary shares

Sale

200

110.9350 USD

$0.0001 ordinary shares

Sale

209

110.6801 USD

$0.0001 ordinary shares

Sale

223

110.5340 USD

$0.0001 ordinary shares

Sale

232

110.7613 USD

$0.0001 ordinary shares

Sale

300

110.3500 USD

$0.0001 ordinary shares

Sale

300

110.4866 USD

$0.0001 ordinary shares

Sale

378

110.5516 USD

$0.0001 ordinary shares

Sale

400

110.9475 USD

$0.0001 ordinary shares

Sale

432

110.9446 USD

$0.0001 ordinary shares

Sale

500

110.9220 USD

$0.0001 ordinary shares

Sale

500

110.7795 USD

$0.0001 ordinary shares

Sale

505

110.7500 USD

$0.0001 ordinary shares

Sale

560

110.5267 USD

$0.0001 ordinary shares

Sale

561

110.3826 USD

$0.0001 ordinary shares

Sale

598

110.5269 USD

$0.0001 ordinary shares

Sale

600

110.5000 USD

$0.0001 ordinary shares

Sale

635

110.3410 USD

$0.0001 ordinary shares

Sale

815

110.3972 USD

$0.0001 ordinary shares

Sale

905

110.4600 USD

$0.0001 ordinary shares

Sale

977

110.9370 USD

$0.0001 ordinary shares

Sale

1,205

110.9390 USD

$0.0001 ordinary shares

Sale

1,240

110.5075 USD

$0.0001 ordinary shares

Sale

1,300

110.9107 USD

$0.0001 ordinary shares

Sale

1,335

110.2867 USD

$0.0001 ordinary shares

Sale

1,368

110.3337 USD

$0.0001 ordinary shares

Sale

1,400

110.9000 USD

$0.0001 ordinary shares

Sale

1,550

110.2544 USD

$0.0001 ordinary shares

Sale

1,644

110.2500 USD

$0.0001 ordinary shares

Sale

1,750

110.7414 USD

$0.0001 ordinary shares

Sale

1,954

110.8142 USD

$0.0001 ordinary shares

Sale

2,119

110.5309 USD

$0.0001 ordinary shares

Sale

2,158

110.9155 USD

$0.0001 ordinary shares

Sale

2,207

110.5883 USD

$0.0001 ordinary shares

Sale

2,690

110.9396 USD

$0.0001 ordinary shares

Sale

2,727

110.4728 USD

$0.0001 ordinary shares

Sale

3,871

110.6635 USD

$0.0001 ordinary shares

Sale

4,231

110.4429 USD

$0.0001 ordinary shares

Sale

4,398

110.9428 USD

$0.0001 ordinary shares

Sale

4,471

110.5632 USD

$0.0001 ordinary shares

Sale

6,169

110.8747 USD

$0.0001 ordinary shares

Sale

7,130

110.8835 USD

$0.0001 ordinary shares

Sale

7,288

110.6395 USD

$0.0001 ordinary shares

Sale

8,003

110.4700 USD

$0.0001 ordinary shares

Sale

9,529

110.6112 USD

$0.0001 ordinary shares

Sale

11,430

110.4629 USD

$0.0001 ordinary shares

Sale

12,725

110.6741 USD

$0.0001 ordinary shares

Sale

17,427

110.4000 USD

$0.0001 ordinary shares

Sale

21,087

110.4955 USD

$0.0001 ordinary shares

Sale

34,049

110.6443 USD

$0.0001 ordinary shares

Sale

34,914

110.7480 USD

$0.0001 ordinary shares

Sale

50,000

110.2897 USD

$0.0001 ordinary shares

Sale

68,000

110.6917 USD

$0.0001 ordinary shares

Sale

105,000

110.7652 USD

(b)

Derivatives transactions (other than option transactions)

Product Name

Nature of transaction

Number of relevant securities

Price per unit

(c)

Options transactions in respect of existing securities

(i)

Writing, selling, purchasing or varying

Class of relevant security

Product description

Writing, purchasing, selling, varying etc

Number of securities to which option relates

Exercise price per unit

Type

Expiry date

Option money paid/ received per unit

(ii)

Exercising

Product name

Number of securities

Exercise price per unit

(d)

Other dealings (including transactions in respect of new securities) (Note 4)

Nature of transaction

Details

Price per unit (if applicable)

4.

OTHER INFORMATION

Agreements, arrangements or understandings relating to options or derivatives

Full details of any agreement, arrangement or understanding between the person disclosing and any other person relating to the voting rights of any relevant securities under any option referred to on this form or relating to the voting rights or future acquisition or disposal of any relevant securities to which any derivative referred to on this form is referenced. If none, this should be stated.

NONE

Is a Supplemental Form 8 (Open Positions) attached?

YES

Date of disclosure:

11 May 2023

Contact name:

Large Holdings Regulatory Operations

Telephone number:

020 3134 7213

If a connected EFM, name of offeree/offeror with which connected

If a connected EFM, state nature of connection

SUPPLEMENTAL FORM 8

IRISH TAKEOVER PANEL

DISCLOSURE UNDER RULE 8.1 AND RULE 8.3 OF THE IRISH TAKEOVER PANEL

ACT, 1997, TAKEOVER RULES, 2007 (AS AMENDED)

DETAILS OF OPEN POSITIONS

(This form should be attached to Form 8.1(a) & (b)(i), Form 8.1(b)(ii) or Form 8.3, as

appropriate)

OPEN POSITIONS

Class of relevant security

Product Description

Writing, purchasing, selling, varying etc

Number of securities to which option relates

Exercise price per unit

Type

Expiry date

$0.0001 ordinary shares

Put Options

Written

495,500

100

American

16 Jun 2023

$0.0001 ordinary shares

Put Options

Written

150,000

090

American

19 May 2023

$0.0001 ordinary shares

Put Options

Purchased

-65,000

095

American

19 May 2023

$0.0001 ordinary shares

Put Options

Purchased

-67,300

110

American

19 May 2023

$0.0001 ordinary shares

Put Options

Purchased

-25,000

085

American

19 May 2023

$0.0001 ordinary shares

Put Options

Purchased

-250,000

080

American

16 Jun 2023

$0.0001 ordinary shares

Put Options

Written

250,000

105

American

16 Jun 2023

$0.0001 ordinary shares

Put Options

Written

10,200

080

American

18 Aug 2023

$0.0001 ordinary shares

Put Options

Written

65,000

105

American

19 May 2023

$0.0001 ordinary shares

Put Options

Written

400,000

100

American

18 Aug 2023

$0.0001 ordinary shares

Put Options

Purchased

-800,000

080

American

18 Aug 2023

$0.0001 ordinary shares

Put Options

Written

162,000

105

American

21 Jul 2023

$0.0001 ordinary shares

Put Options

Purchased

-10,200

100

American

18 Aug 2023

$0.0001 ordinary shares

Put Options

Purchased

-162,000

090

American

21 Jul 2023