28th Feb 2007 17:48
Notification of major interests in shares
28 February 2007
1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:
Shire plc
2. Reason for the notification State Yes/No An acquisition or disposal of voting rights An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Yes Other (please specify):
3. Full name of person(s) subject to the notification Legal & General obligation:
Group Plc (L&G) 4. Full name of shareholder(s) (if different from 3.): N/A 5. Date of the transaction (and date on which the N/A threshold is crossed or reached if different): 6. Date on which issuer notified: 16 February 2007 7. Threshold(s) that is/are crossed or reached: Above 3% (L&G) 8. Notified details:
A: Voting rights attached to shares
Class/type of Situation previous Resulting situation after the triggering
shares to transaction if possible the Triggering using the transaction ISIN CODE Number Number Number Number of voting % of voting of of of rights rights Shares Voting shares Rights Direct Direct Indirect Direct Indirect GBP Ord. 0.05 14,711,691 3.08% 17,136,981 17,136,981 3.349 (Under S-198 on 02/02/04) ADR Shares 7,299 21,897 0.004 B: Financial Instruments
Resulting situation after the triggering transaction
Type of Expiration Exercise/ Number of voting % of financial date Conversion rights that may be voting instrument Period/ Date acquired if the rights instrument is exercised/converted Total (A+B) Number of voting rights % of voting rights 17,158,878 3.35
9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:
Legal & General Group Plc (Direct and Indirect) (Group)
Legal & General Investment Management (Holdings) Limited (LGIMH) (Direct and Indirect)
Legal & General Investment Management Limited (Indirect) (LGIM)
Legal & General Group Plc (Direct) (L&G) (17,158,878 - 3.35% = LGAS, LGPL &
PMC)
Legal & General Investment Management (Holdings) Limited (Direct) (LGIMHD)
Legal & General Insurance Holdings Limited (Direct) (LGIH) Legal & General Assurance (Pensions Management) Limited (PMC) Legal & General Assurance Society Limited (LGAS & LGPL) Legal & General Pensions Limited (Direct) (LGPL) Proxy Voting:10. Name of the proxy holder: N/A 11. Number of voting rights proxy holder will cease to hold: N/A 12. Date on which proxy holder will cease to hold voting N/A rights: 13. Additional information: Notification using the total voting rights figures of 511,667,558 First notification under the DTR Sourcebook 14. Contact name: Helen Lewis 15. Contact telephone number: 020 7528 6742
Contact at Shire plc: Vivienne Hemming, Deputy Company Secretary, 01256 894276
For further information please contact:
Investor Relations Clĩa Rosenfeld (Rest of the World) +44 1256 894 160 Eric Rojas (North America) +1 484 595 8252 Notes to editorsSHIRE PLC
Shire's strategic goal is to become the leading specialty pharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on attention deficit and hyperactivity disorder (ADHD), human genetic therapies (HGT), gastrointestinal (GI) and renal diseases. The structure is sufficiently flexible to allow Shire to target new therapeutic areas to the extent opportunities arise through acquisitions. Shire believes that a carefully selected portfolio of products with a strategically aligned and relatively small-scale sales force will deliver strong results.
Shire's focused strategy is to develop and market products for specialty physicians. Shire's in-licensing, merger and acquisition efforts are focused on products in niche markets with strong intellectual property protection either in the US or Europe.
For further information on Shire, please visit the Company's website: www.shire.com.
Hampshire International Business Park Chineham Basingstoke Hampshire RG24 8EP United Kingdom Tel +44 (0)1256 894000 Fax +44 (0)1256 894708 www.shire.com Press Release
Registered in England 5492592Registered Office as above
LEGAL & GENERAL GROUP PLCRelated Shares:
Legal & GeneralShire