Holding(s) in Company

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached[ii]:

Biofutures International Plc

2. Reason for the notification  (please tick the appropriate box or boxes)

An acquisition or disposal of voting rights

x

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify): Fresh Start notification in the context of reallocation and threshold related recalculation of reportable holdings due to the new formation of Allianz Group and Commerzbank Group

3. Full name of person(s) subject to the notification obligation[iii]:

Allianz SE

4. Full name of shareholder(s) (if different from 3.)[iv]:

Allianz Insurance plc

5. Date of the transaction (and date on which the threshold is crossed or reached if different)[v]:

12 March 2013

6. Date on which issuer notified:

14 March 2013

7. Threshold(s) that is/are crossed or reached:

7%, 6%, 5%, 4%, 3%

8. Notified details:

A: Voting rights attached to shares

Class/type of shares

 if possible using the ISIN CODE

Situation previous to the Triggering transaction [vi]

Resulting situation after the triggering transaction[vii]

Number of Voting Rights viii

Number of shares

Number of voting rights ix

% of voting rights

Direct x

Indirect xi

Direct

Indirect

GB00B12B4T47

11,650,000

11,650,000

< 3%

B: Financial Instruments

Resulting situation after the triggering transaction xii

Type of financial instrument

Expiration date xiii

Exercise/ Conversion Period/ Date xiv

Number of voting rights that may be acquired if the instrument is exercised/ converted.

% of voting rights

Total (A+B)

Number of voting rights

% of voting rights

< 3%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable xv:

Allianz SE is the ultimate holding company of Allianz Europe B.V., which is the major holding company of Allianz Europe Ltd, which is the major holding company of Allianz (UK) Limited, which is the holding company of Allianz Holdings Plc, which is the major holding company of Allianz Insurance Plc.

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14. Contact name:

 Annette Bartram, Allianz SE

15. Contact telephone number:

+49 89 38 00-14391