Holding(s) in Company

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Allergy Therapeutics plc

2. Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

X

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

X

3. Full name of person(s) subject to the notification obligation:

Highclere International Investors Limited

4. Full name of shareholder(s) (if different from 3.):

The Highclere International Investors International Smaller Companues Fund

The Highclere (Jesrsey) International Investors International Smaller Companues Fund

5. Date of the transaction and date on which the threshold is crossed or reached:

9 March 2010

6. Date on which issuer notified:

9 March 2010

7. Threshold(s) that is/are crossed or reached:  Above 4%

8. Notified details

A: Voting rights attached to shares

Class/type of shares

if possible using the ISIN CODE

Situation previous to the Triggering transaction

Resulting situation after the triggering transaction

Number of Voting Rights

Number of shares

Number of voting rights

% of voting rights

Direct

Indirect

Direct

Indirect

GB00B02LCQ05

11,683,057 11,683,057

12,851,363

12,85,363

4.15%

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ Conversion Period/ Date

Number of voting rights that may be acquired if the instrument is exercised/ converted

% of voting rights

N/A

N/A

N/A

N/A

N/A

Total (A+B)

Number of voting rights

% of voting rights

12,851,363

4.15%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:

Not Applicable

Proxy Voting:

10. Name of the proxy holder:

Highclere International Investors Limited

11. Number of voting rights proxy holder will cease to hold:

N/A

12. Date on which proxy holder will cease to hold voting rights:

N/A

13. Additional information:

Highclere International Investors Limited ("Highclere") acts as an investment manager for the clients detailed in Question 4 above (our "Clients"). In acting for our Clients, Highclere are given full discretion over their investments and are empowered to vote on their behalf. However, we do not act as our Client's custodian and therefore shares are not held in our name but in the nominee name of their custodian bank

14. Contact name

Fergus Gilmore, Compliance Officer

15. Contact telephone number

0207-258-9845