Holding(s) in Company - Replacement

1. Identity of the issuer or the underlying issuerof existing shares to which voting rights areattached: ii

Immunodiagnostic Systems Holdings Plc

GB00B01YZ052

2 Reason for the notification (please tick the appropriate box or boxes): Error in Box 10 corrected and now states N/A

An acquisition or disposal of voting rights

X

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

3. Full name of person(s) subject to thenotification obligation: iii

SFM UK Management LLP

4. Full name of shareholder(s)  (if different from 3.):iv

Quantum Partners LP

5. Date of the transaction and date onwhich the threshold is crossed orreached: v

October 6th, 2015

6. Date on which issuer notified:

October 8th, 2015 (correction issued October 21st, 2015)

7. Threshold(s) that is/are crossed orreached: vi, vii

3%

8. Notified details:

A: Voting rights attached to shares viii, ix

Class/type ofshares

if possible usingthe ISIN CODE

Situation previousto the triggeringtransaction

Resulting situation after the triggering transaction

NumberofShares

NumberofVotingRights

Numberof shares

Number of votingrights

% of voting rights x

Direct

Direct xi

Indirect xii

Direct

Indirect

GB00B01YZ052

779,278

779,278

1,031,343

1,031,343

NA

3.5%

NA

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Expirationdate xiii

Exercise/Conversion Period xiv

Number of votingrights that may beacquired if theinstrument isexercised/ converted.

% of votingrights

N/A

N/A

N/A

N/A

N/A

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments xv, xvi

Resulting situation after the triggering transaction

Type of financialinstrument

Exercise price

Expiration date xvii

Exercise/Conversion period xviii

Number of voting rights instrument refers to

% of voting rights xix, xx

N/A

N/A

N/A

N/A

N/A

Nominal

Delta

N/A

N/A

Total (A+B+C)

Number of voting rights

Percentage of voting rights

1,031,343

3.5%

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable: xxi

This statement relates to common shares held for the account of Quantum Partners LP, a Cayman Islands

exempted limited partnership ("Quantum Partners"). SFM UK Management LLP, a sub-advisor to Soros

Fund Management LLC, serves as investment manager to Quantum Partners and has been granted

investment discretion over portfolio investments, including the common shares, held for the account of

Quantum Partners.

Proxy Voting:

10. Name of the proxy holder:

N/A

11. Number of voting rights proxy holder will ceaseto hold:

N/A

12. Date on which proxy holder will cease to holdvoting rights:

N/A

13. Additional information:

None

14. Contact name:

Jade Cornell

Compliance officer

15. Contact telephone number:

020 7758 4800