28th Feb 2007 17:46
Notification of major interests in shares
28 February 2007
1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:
Shire plc
2. Reason for the notification State Yes/No An acquisition or disposal of voting rights An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Yes Other (please specify):
3. Full name of person(s) subject to the notification obligation: Fidelity
International Limited (FIL) 4. Full name of shareholder(s) (if different from 3.): See attached schedule
5. Date of the transaction (and date on which the threshold is Revised due crossed
to DTR rules or reached if different): 6. Date on which issuer notified: 27 February 2007 7. Threshold(s) that is/are crossed or reached: 8. Notified details:
A: Voting rights attached to shares
Class/type of Situation previous to Resulting situation after the triggering shares the Triggering transaction if possible transaction using the ISIN CODE Number Number Number Number of voting % of voting of of of rights rights Shares Voting shares Rights Direct Direct Indirect Direct Indirect GB00B0KQX869 26,759,374 26,759,374 26,759,374 5.23%
B: Financial Instruments
Resulting situation after the triggering transaction
Type of Expiration Exercise/ Number of voting % of financial date Conversion rights that may be voting instrument Period/ Date acquired if the rights instrument is exercised/converted Total (A+B) Number of voting rights % of voting rights 26,759,374 5.23%
9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:
See attached schedule Proxy Voting:10. Name of the proxy holder: Fidelity International Limited (FIL) 11. Number of voting rights proxy holder will cease to hold: N/A 12. Date on which proxy holder will cease to hold voting N/A rights: 13. Additional information: As discussed with the FSA, prior to the implementation of the EU Transparency Directive, we aggregated the interests in the shares of FMR Corp (FMR) and Fidelity International Limited (FIL) together for the purposes of shareholder reporting. According to the new DTR rules we are now reporting the indirect holdings of FMR and FIL separately. A separate notification is being submitted for FILFMR Corp. Please note these holdings are correct as of close of business 26 February 2007. 14. Contact name: Sophie Hughes 15. Contact telephone number: 01737 836713
(Contact at Shire plc: Vivienne Hemming, Deputy Company Secretary, 01256 894276)
Schedule:
Shares Held Nominee Management Company
23,500 TRUST&CUST SVCS BK LTD, TOKO FIJ
27,200 STATE STREET HONG KONG FIA(K)L
372,030 STATE STR BK AND TR CO LNDN (S FPM
46,700 STATE STR BK AND TR CO LNDN (S FIL
977,197 NORTHERN TRUST LONDON FPM
170,500 NORTHERN TRUST LONDON FIL
52,800 NORTHERN TRUST CO FIL
18,200 NORDDEUTSCHE LANDERSBANK FIL
46,100 NOMURA TEST AND BANKING FIJ
119,300 MIDLAND SECURITIES SERVICES FPM
472,900 MELLON BANK FPM
88,700 MASTER TRUST BANK OF JAPAN FIJ
279,800 JPMORGAN, BOURNEMOUTH FIL
922,028 JPMORGAN, BOURNEMOUTH FPM
10,770,619 JPMORGAN, BOURNEMOUTH FISL
3,417,582 JPMORGAN, BOURNEMOUTH FIL
987,772 JPMORGAN, BOURNEMOUTH FII
12,200 DEXIA PRIVATBANK FPM
23,300 CHASE MANHTTN BK AG FRNKFRT (S FPM
65,400 BROWN BROTHERS HARRIMAN AND CO FIL
5,471,451 BROWN BROS HARRIMN LTD LUX FIL
702,230 BNP PARIBAS, PARIS FIGEST
110,300 BNP PARIBAS, PARIS (C) FIL
266,500 BERMUDA TRUST FAR EAST HK FIM HK
686,800 BANK OF NEW YORK EUROPE LDN FII
628,265 BANK OF NEW YORK BRUSSELS FPM
Fidelity International Limited (FIL) is the parent holding company for various direct and indirect subsidiaries, including Fidelity Fund Management Limited (FFML), Fidelity Fund Management Limited (FFML), Fidelity Investment Services Ltd (FISL), Fidelity Gestion (FIGEST), Fidelity Investments Advisory (Korea) Limited (FIAKL), Fidelity Investments Management (Hong Kong) Limited (FIMHK), Fidelity Pension Management (FPM), Fidelity Investments Japan (FLJ) and Fidelity Investments International (FII), investment managers for various non-US investment companies and institutional clients.
For further information please contact:
Investor Relations Clĩa Rosenfeld (Rest of the World) +44 1256 894 160 Eric Rojas (North America) +1 484 595 8252 Notes to editorsSHIRE PLC
Shire's strategic goal is to become the leading specialty pharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on attention deficit and hyperactivity disorder (ADHD), human genetic therapies (HGT), gastrointestinal (GI) and renal diseases. The structure is sufficiently flexible to allow Shire to target new therapeutic areas to the extent opportunities arise through acquisitions. Shire believes that a carefully selected portfolio of products with a strategically aligned and relatively small-scale sales force will deliver strong results.
Shire's focused strategy is to develop and market products for specialty physicians. Shire's in-licensing, merger and acquisition efforts are focused on products in niche markets with strong intellectual property protection either in the US or Europe.
For further information on Shire, please visit the Company's website: www.shire.com.
Hampshire International Business Park Chineham Basingstoke Hampshire RG24 8EP United Kingdom Tel +44 (0)1256 894000 Fax +44 (0)1256 894708 www.shire.com Press Release
Registered in England 5492592Registered Office as above
SHIRE PLCRelated Shares:
Shire