Holding(s) in Company

TR-1: Notifications of Major Interests in Shares

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Immunodiagnostic Systems Holdings plc

2. Reason for notification (yes/no)

An acquisition or disposal of voting rights

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached 

An event changing the breakdown of voting rights

Other (please specify): This notification corrects for an earlier announcement, released on 10 December 2008, regarding Forum's holding in the Company. Following the issue of equity by the Company, as announced on 10 December 2008, Forum actually held 4,221,064 shares in the Company which represents 15.98% of the Company's issued share capital, and not 4,221,064 shares (16.52%) as stated in the announcement. All other information in that announcement relating to Forum remains correct.

Yes

3. Full name of person(s) subject to notification obligation:

Forum Venture Capital GmbH

4. Full name of shareholder(s) (if different from 3):

5. Date of transaction (and date on which the threshold is crossed or reached if different):

n/a

6. Date on which issuer notified:

20 January 2009

7. Threshold(s) that is/are crossed or reached:

n/a

8. Notified details:

A: Voting rights attached to shares

Class/type of shares

If possible use ISIN code

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Number of shares

Number of voting rights

Number of shares

Number of voting rights

Percentage of voting rights

Direct

Indirect

Direct

Indirect

GB00B01YZ052

3,719,526

3,719,526

4,221,064

4,221,064

15.98%

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ conversion period/date 

No. of voting rights that may be acquired (if the instrument exercised/converted)

Percentage of voting rights

Total (A+B)

Number of voting rights

Percentage of voting rights

9. Chain of controlled undertakings through which the voting rights and / or the financial instruments are effectively held; if applicable xv:

N/A

Proxy Voting:

10. Name of proxy holder:

N/A

11. Number of voting rights proxy holder will cease to hold:

N/A

12. Date on which proxy holder will cease to hold voting rights:

N/A

13. Additional information:

14 Contact name:

Burkhard Wittek

15. Contact telephone name:

+49 (0) 89 27 37 49-0