29th Jul 2011 16:00
Notification of major interests in shares
July 29, 2011 - Shire plc
1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:
Shire plc 2. Reason for the notification State Yes/No An acquisition or disposal of voting rights Yes
An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached
An event changing the breakdown of voting rights Other (please specify):
3. Full name of person(s) subject to the notification Capital Group obligation:
International, Inc 4. Full name of shareholder(s) (if different from 3.): 5. Date of the transaction (and date on which the 27 July 2011 threshold is crossed or reached if different): 6. Date on which issuer notified: 29 July 2011 7. Threshold(s) that is/are crossed or reached: Below 4% 8. Notified details:
A: Voting rights attached to shares
Situation previous to Resulting situation after the triggering the Triggering transaction transaction Class/type of shares Number Number Number Number of voting % of voting if possible of of of rights rights using the ISIN Shares Voting shares CODE Rights Direct Indirect Direct Indirect Direct Indirect Ordinary 14,121,202 14,121,202 13,927,202 13,927,202 2.4766% (JE00B2QKY057)
ADR 2,812,773 8,438,319 2,812,098 8,436,294 1.5002%
(US82481R1068) B: Financial Instruments
Resulting situation after the triggering transaction
Type of Expiration Exercise/ Number of voting % of financial date Conversion rights that may be voting instrument Period/ Date acquired if the rights instrument is exercised/converted n/a Total (A+B)
Number of voting rights % of voting rights
22,363,496 3.9768%
9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:
Number of Percent of Shares Outstanding Capital Group International, Inc. ("CGII") 22,363,496 3.9768% holdings Holdings by CGII Management Companies and Funds: • Capital Guardian Trust Company 17,944,348 3.1909% • Capital International Limited 1,305,341 0.2321% • Capital International Srl 513,000 0.0912% • Capital International, Inc. 2,600,807 0.4625% Proxy Voting:10. Name of the proxy holder: N/A
11. Number of voting rights proxy holder will cease to hold: N/A
12. Date on which proxy holder will cease to hold voting rights: N/A
13. Additional information: Notification using the total voting rights figures of 562,353,761 14. Contact name: Vivien Tan 15. Contact telephone (213) 486 9200 number:
Contact at Shire plc: Tony Guthrie, Deputy Company Secretary, +44 1256 894746
For further information please contact:
Investor Relations Eric Rojas [email protected] +1 781 482 0999 Sarah Elton-Farr [email protected] +44 1256 894157 Notes to editors SHIRE PLC
Shire's strategic goal is to become the leading specialty biopharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on attention deficit hyperactivity disorder (ADHD), human genetic therapies (HGT) and gastrointestinal (GI) diseases as well as opportunities in other therapeutic areas to the extent they arise through acquisitions. Shire's in-licensing, merger and acquisition efforts are focused on products in specialist markets with strong intellectual property protection and global rights. Shire believes that a carefully selected and balanced portfolio of products with strategically aligned and relatively small-scale sales forces will deliver strong results.
For further information on Shire, please visit the Company's website: www.shire.com
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