Holding(s) in Company

For filings with the FSA include the annexFor filings with issuer exclude the annex

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi

1. Identity of the issuer or the underlyingissuer of existing shares to which votingrights are attached: ii Verona Pharma2. Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

An acquisition or disposal of qualifying financial instruments whichmay result in the acquisition of shares already issued to which votingrights are attached

An acquisition or disposal of instruments with similar economic effectto qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify): Increase in Total Voting Rights

X

3. Full name of person(s) subject to the Investec Wealth & Investment Limitednotification obligation: iii

4. Full name of shareholder(s) N/A

(if different from 3.):iv

5. Date of the transaction and date on 14th February 2013which the threshold is crossed orreached: v6. Date on which issuer notified: 18th February 20137. Threshold(s) that is/are crossed or From 11% to 10%reached: vi, vii8. Notified details:

A: Voting rights attached to shares viii, ix

Class/type of Situation previous Resulting situation after the triggeringtransactionshares to the triggering transactionif possibleusingthe ISIN CODE Number Number Number Number of voting % of voting rights of of of shares rights x Shares Voting Rights Direct Direct xi Indirect Direct Indirect xiiOrdinary Shares 36,382,500 36,382,500 36,382,500 10.82%GB00B06GSH43

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial Expiration Exercise/ Number of voting % of votinginstrument date xiii Conversion Period xiv rights that may be rights acquired if the instrument is exercised/ converted.

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments xv, xvi

Resulting situation after the triggering transaction

Type of financial Exercise Expiration Exercise/ Number of voting rights % of votinginstrument price date xvii Conversion period

instrument refers to rights xix, xx

xviii Nominal DeltaTotal (A+B+C)Number of voting rights Percentage of voting rights36,382,500 10.82%

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable: xxiClient holdings registered in the name of Nominee companies 100% owned byInvestec Wealth & Investment Limited.

Proxy Voting:10. Name of the proxy holder: N/A

11. Number of voting rights proxy holder will cease to hold: N/A

12. Date on which proxy holder will cease to hold voting rights: N/A

13. Additional information: N/A14. Contact name: Phil Beardwell Chartered FCSI Senior Compliance Manager15. Contact telephone number: 020 7597 1356

Note: Annex should only be submitted to the FSA not the issuer

Annex: Notification of major interests in sharesxxii

A: Identity of the persons or legal entity subject to the notification obligationFull name

Investec Wealth & Investment

Limited

(including legal form of legal entities)

Contact address 2 Gresham Street

(registered office for legal entities) London

EC2V 7QPPhone number & email 0113 236 4171 [email protected] useful information Mike Rigby

(at least legal representative for legal (Head of Compliance)persons)

B: Identity of the notifier, if applicableFull name Philip Martin BeardwellContact address 2 Gresham Street London EC2V 7QNPhone number & email 020 7597 1356 [email protected] useful information Senior Compliance Manager(e.g. functional relationship with theperson or legal entity subject to thenotification obligation)

C: Additional information

For notes on how to complete form TR-1 please see the FSA website.