8th Sep 2008 16:00
Notification of major interests in shares
Basingstoke, UK and Philadelphia, US - September 8, 2008 - Shire Limited , the global specialty biopharmaceutical company
1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:
Shire Limited
2. Reason for the notification State Yes/No An acquisition or disposal of voting rights Yes An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Other (please specify): 3. Full name of person(s) subject to the notification Legal & General obligation: Group Plc (L&G) Legal & General Investment Management Limited (LGIM)
4. Full name of shareholder(s) (if different from 3.): Legal & General Assurance (Pensions Management) Limited (PMC) 5. Date of the transaction (and date on which the 4 September 2008 threshold is crossed or reached if different): 6. Date on which issuer notified: 5 September 2008 7. Threshold(s) that is/are crossed or reached: Below 5% (Group)
Below 5% (LGIM) From 5% - 4% (L&G) 8. Notified details:
A: Voting rights attached to shares
Class/type Situation previous to Resulting situation after the triggering
of shares the Triggering transaction if possible transaction using the ISIN CODE Number Number Number Number of voting % of voting of of of rights rights Shares Voting shares Rights Direct Direct Indirect Direct Indirect ORD 31,053,995 31,053,995 Below 5% (LGIM) GBP 0.05 (LGIM) (LGIM) ORD 28,039,788 28,039,788 23,985,756 23,985,756 4.28 GBP 0.05 (ORD) (ORD) (L&G) (L&G) ADR 7,299 21,897 7,299 21,897 0.003 (ADR) (ADR)
B: Financial Instruments
Resulting situation after the triggering transaction
Type of Expiration Exercise/ Number of voting % of financial date Conversion rights that may be voting instrument Period/ Date acquired if the rights instrument is exercised/converted Total (A+B) Number of voting rights % of voting rights 24,007,653 (L&G) 4.28 (L&G) Below 5% (LGIM)
9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:
Legal & General Group Plc (Direct and Indirect) (Group) (Below 5%)
Legal & General Investment Management (Holdings) Limited (LGIMH) (Direct and Indirect) (Below 5%)
Legal & General Investment Management Limited (Indirect) (LGIM) (Below 5%) Legal & General Group Plc (Direct) (L&G) (24,007,653 - 4.28 % = LGAS, LGPL & PMC)
Legal & General Investment Management (Holdings) Limited (Direct) (LGIMHD) (21,131,760 -3.77 % = PMC)
Legal & General Insurance Holdings Limited (Direct) (LGIH)
Legal & General Assurance (Pensions Management) Limited (PMC) (21,131,760 -3.77 % = PMC)
Legal & General Assurance Society Limited (LGAS & LGPL) Legal & General Pensions Limited (Direct) (LGPL)
Proxy Voting:10. Name of the proxy holder: N/A
11. Number of voting rights proxy holder will cease to hold: N/A 12. Date on which proxy holder will cease to hold voting N/A
rights: 13. Additional information: Notification using the total voting rights figures of 559,980,974 14. Contact name: Helen Lewis (LGIM)
15. Contact telephone number: 020 3124 3851
Contact at Shire Limited: Tony Guthrie, Deputy Company Secretary, 01256 894746
For further information please contact:
Investor Relations Clĩa Rosenfeld (Rest of the World) +44 1256 894 160 Eric Rojas (North America) +1 484 595 8252 Notes to editorsSHIRE LIMITED
Shire's strategic goal is to become the leading specialty biopharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on attention deficit and hyperactivity disorder (ADHD), human genetic therapies (HGT), gastrointestinal (GI) and renal diseases. The structure is sufficiently flexible to allow Shire to target new therapeutic areas to the extent opportunities arise through acquisitions. Shire's in-licensing, merger and acquisition efforts are focused on products in niche markets with strong intellectual property protection either in the US or Europe. Shire believes that a carefully selected portfolio of products with strategically aligned and relatively small-scale sales forces will deliver strong results.
For further information on Shire, please visit the Company's website: www.shire.com.
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